1.3- Dioxolane carbohydrate synthesis

Since 1895, when Emil Fischer1 described the reaction of aldehydes and ketones with glycoses, an impressive part of the chemistry of carbohydrates has dealt with acetals, and especially cyclic acetals (mainly 1,3-dioxolanes and 1,3-dioxanes). There are probably relatively few studies on the synthetic chemistry of monosaccharides that do not describe at least one acetal of a carbohydrate, be it for routine protection, or for use in an original synthesis. At least, in this Series, three articles have appeared on the cyclic acetals of the aldoses and aldosides2,3 and of the ketoses4, one article dealt with acetals of tetri-... 

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