2.5- DioxO-l-phenyl

Unsubstituierte Imidazole konnen durch Umsetzungmit Kaliumcarbonat und Kohlendioxid unter Druck im Autoklaven bei 150° zu 4(5)-Carboxy-imidazolen carboxyliert werden701. Die Umsetzung von 2,5-Dioxo-l-phenyl-imidazolidin mit Methoxy -methoxycarbonyloxy-magnesium fuhrt zu 4-Carboxy-2,5-dioxo-l-phenyl-imidazolidin (s. Bd.E5/l, S.328) ... 

A slight excess of ethereal diazomethane soln. added with stirring and ice-cooling to an ethereal suspension of 1-phenylquinisatin, and the product isolated after 0.5 hr. -> 3-hydroxy-2,4-dioxo-3-diazomethyl-l-phenyl-l,2,3,4-tetrahydroquinoline (Y 80%) added to methanol or ethanol, and treated with water after ca. 15 min. -> 4-hydroxy-2,5-dioxo-l-phenyl-2,5-dihydro-lH-l-benzazepine (Y 84%). B. Eistert and P. Donath, B. 103, 993 (1970). 

X-Ray crystallographic analysis of 4-(2,4-dinitrophenyl)-2,5-dioxo-8-phenyl-l,2,3,4,5,6-hexahydropyrido[2,3-pyrida-zine 7 is in agreement with the semi-empirical molecular orbital calculation (AMI) <2000T2473>. 

Dioxo-l-[2-fluoro-7-(3-ineiho.xy-phenyl)-3-oxo-heptyl]-1 -methyl-EI0h,. 450 (2-F —cn + RH)... 

Hexen 3,5-Dioxo-l-phenyl- El 9b, 1261 (Hydroxy-carben - Keton) Flydroperoxid l-(2-Naphthyl)-ethyl-E13/1, 161 (O-Ac - O-OH) Inden... 

Michael addition of 5-(2-alkyl-l-methylhydrazino)-2-phenylpyridazin-3(2//)-ones to dimethyl acetylenedicarboxylate produces 5- 2-alkyl-2-[l,2-bis(methoxycarbonyl)vinyl]-l-methylhydrazi-no -2-phenylpyridazin-3(2//)-ones, which cyclize on heating in Tetralin at 220 °C by a Diels -Reese reaction68 to give methyl 3-(alkylamino)-l-methyl-2,5-dioxo-6-phenyl-l,2,5,6-tetrahy-dropyrido[2,3-rf]pyridazine-4-carboxylates l.69... 

Auf die Verwendbarkeit von (3/ S,6S)-2,5-Dioxo-3-phenyl-morpholin (aus DL-Phenylgly-cin und L-a-Acetoxy-carbonsaure-chloriden) ffir die Herstellung optisch aktiver oc-alky-lierter Phenyl-162 und (2-Furyl)-glycine163 sei hingewiesen. Ahnlich den fur 2,5-Di-... 

The examples of the oxaphospholane compound are 2-methyl-2,5-dioxo-l-oxa-2-phospholane and 2-phenyl-2,5-dioxo-l-oxa-2-phospholane. The oxaphospholane compounds are used alone or in combination. 

Other Names Xanthylium, 3,6-diamino-9-[2-carboxy (or 5)-[[(2,5-dioxo-l-pyrrolidinyl)oxy]carbonyl]phenyl]-4,5-disulfo-, iimer salt, dilithium salt Alexa 488 Alexa 488 succinimidyl ester Alexa Fluor 488 Alexa Fluor 488 NHS Alexa Fluor 488 NHS ester Alexa Fluor 488 carboxylic acid SE Alexa Fluor 488 carboxylic acid succinimidyl ester Alexa Fluor 488 SE Alexa Eluor 488 succinimidyl ester... 

CA Index Name [l]Benzopyrano[3,2-g]quinolin-ll-ium, 9-amino-6-[2-carboxy-4(or 5)-[[(2,5-dioxo-l-pyrrolidinyl)-oxy]carbonyl]-phenyl]-l,2,3,4-tetrahydro-2, 2,4-trimethyl-10,12-disulfo-, inner salt... 

CA Index Name Xanthylium, 9-[2-[[4-[[(2,5-dioxo-l-pyrrolidinyl)oxy] -carbonyl] -1 -piperidinyl]sulfonyl] phenyl]-3,6-bis[methyl(4-sulfophenyl)amino]-, chloride (1 1)... 

In AcetonitrilundTctraathylammoniumperchlorat als Leitsalz erhalt manbei —2 V an Quecksilber aus l,5-Dioxo-l,5-diphenyl-pentan 1,2-Dihydroxy-1,2-diphenyl-cyclopen-tan (76% d.Th.)2, vgI"3 und aus l,6-Dioxo-l,6-bis-[4-hydroxy-phenyl]-hexan /,2-Dihydroxy- 1,2-bis- 4-hydroxy-phenyl]-cyclohexan3 ... 

The potassium salt of 7-methyl-3-phenyl-2,4-dioxo-l,2,3,4-tetrahydropyrido[2,3- pyrimidine-5-carboxylate 153 was condensed with l-bromo-3-chloropropane or 1,4-dibromobutane in anhydrous DMF at room temperature to afford the A-l-alkyl derivatives 154 and 155, respectively <1994FA499>. The corresponding A-l-piperazinylalkyl derivatives of 153 were also prepared in more than 40% yield. Debenzylation of 6-benzyl-3-methylpyrido[4,3-,7 pyrimidine 156 by Pd/C-catalyzed hydrogenolysis in AcOH gave the analogue 157 <1994JHC1569>. 

Die iiber 2-(2,4-Dioxo-1-phenyl-diazetin-l-yl)-l,3,4-oxadiazole beschriebenc Umsetzung mit Aminen zu 5-(3-Aminocarbonyl-ureido)-2-phenyl-l, 3,4-oxadiazolen656 kann auch problemlos ausgehend von 5,7-Dioxo-5,7-dihydro-6H-[Pg.607]

Pentene 1.5-Bis-[4-fluoro-phenyl]-l,5-dioxo-3-phenyl- E7b. 936 (Pyrrylium-Salt/OH )... 

In cyclic sulfoximides such as 3-ethoxy-4,5-dihydro-3-oxo-l-phenyl-and 3,4,5,6-tetrahydro-3,5-dioxo-1 -phenyl-1H-1 A6,2,4-thiadiazine 1 -oxides (46), the C6 proton signals appear at much higher fields [4.35 and 4.9 ppm (2H)] than for aromatic systems [benzene, 7.27 ppm thiophene, 7.2 (C2-H) and 6.95 ppm (C3-H)]. Similarly, the, 3C-NMR signals of the C6 atom appear at higher fields. These facts suggest a degree of ylidic character (77JOC952), which can be demonstrated by the reactivity of such compounds towards electrophiles (see Section III, C,3,f). 

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