2,5-dimethylphenyl-

More information has appeared concerning the nature of the side reactions, such as acetoxylation, which occur when certain methylated aromatic hydrocarbons are treated with mixtures prepared from nitric acid and acetic anhydride. Blackstock, Fischer, Richards, Vaughan and Wright have provided excellent evidence in support of a suggested ( 5.3.5) addition-elimination route towards 3,4-dimethylphenyl acetate in the reaction of o-xylene. Two intermediates were isolated, both of which gave rise to 3,4-dimethylphenyl acetate in aqueous acidic media and when subjected to vapour phase chromatography. One was positively identified, by ultraviolet, infra-red, n.m.r., and mass spectrometric studies, as the compound (l). The other was less stable and less well identified, but could be (ll). 

Other substituted phenyl A/-methylcarbamates that have been used for insect control include metalkamate [8065-36-9] a 1 4 mixture of y -(l-ethylpropyl)-phenyl A[-methylcarbamate [672-04-8] and y -(l-methylbutyl)-phenyl A/-methylcarbamate [2282-34-0], rat oral LD qS 87, 170 mg/kg, used as a soil insecticide MTMC [1129-41 -5], 3-methylphenyl N-methylcarbamate (mp 76°C), rat oral LD q 268 mg/kg, used for rice pests MPMC [2425-10-7], 3,5-dimethylphenyl A/-methylcarbamate (mp 79°C), rat oral LD q 380 mg/kg, used for rice pests TBPMC [780-11-0], 3-/ l -butylphenyl A/-methylcarbamate (mp 140°C), mouse oral LD q 470 mg/kg, for rice pests and butacarb [2655-19-8], 3,5-di-/ l -butylphenyl A/-methylcarbamate (mp 98°C), rat oral LD q >4000 mg/kg, for sheep blowfly larvae control. 

Hydrolysis of trialkyl- and triaryldihaloantimony compounds generally leads to the isolation of compounds of the type (R2 bX)20 rather than compounds of the type R2Sb(OH)X. However, hydroxoiodobis(2,6-dimethylphenyl)antimony [112515-20-5] (2,6(CH2)2CgH2)2Sb(OH)I, (184) and four cyclohexyl compounds have been prepared (185) chlorohydroxotricyclohexylantimony [85362-32-9] C gH ClOSb, bromohydroxotricyclohexylantimony [85362-33-0] C gH BrOSb, acetatohydroxotricyclohexylantimony [85362-34-1] C2QH2y02Sb, and hydroxonitratotricyclohexylantimony [85362-35-2] C,gH34N04Sb. 

Azocin-2( 1H )-one, hexahydro- 1-phenyl-photochemical rearrangement, 7, 656 Azodn-2( 1H )-one, 1,2,7,8-tetrahydro-synthesis, 7, 662 Azocin-5-one IR spectra, 7, 16 transannular interactions, 7, 14 Azocin-5-one, l-(2,4-dimethylphenyl)-IR spectrum, 7, 657 Azocin-5-one, methoxycarbonyl-synthesis, 7, 657 Azocin-5-one, 1-methyl-IR spectrum, 7, 657 synthesis, 7, 657 Azodn-5-one, 1-p-tolyl-IR spectrum, 7, 657 Azocinones... 

The initiation mechanism is well defined because of the recent isolation and spectroscopic characterization of the initial zwitterion from ethyl cyanoacrylate (ECA) and a phosphine [8,9]. Specifically, zwitterion 4 was prepared from the reaction of equimolar amounts of dimethylphenyl phosphine, 5, and ECA, 6,... 

Phenyl, 690 2-Methylphenyl, 691 2,6-Dimethylphenyl, 691 2-Chlorophenyl, 691 4-Chlorophenyl, 691 2,4-Dichlorophenyl, 691... 

Tautomerism involving compounds included in a host molecule (type 6) has been studied, in some cases involving triazoles and pyrazoles [87CL2317 88CL1061 93JCS(CC)1139] [the last reference describes a case of proton transfer for pyrazole included in l,l-di(2,4-dimethylphenyl)but-2-yn-l-ol]. 

Inhibition of human multidrug resistance P-glycoprotein 1 was investigated by analogs of a potent. 5-opioid antagonist, including (35, 1 lu5)-3-[(4-hydroxy-2,6-dimethylphenyl)methyl]-11,11 u-dihydro-2//-pyrazino[l, 1-b] isoquinoline-l,4(3//,6//)-dione (OIMIIO). Opioid antagonist activity of... 

Therapeutic Function Local anesthetic, antiarrhythmic Chemical Name 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide Common Name Lignocaine... 

Chemical Name 4-[4,4-Bis(4-fluorophenyl)butvU -N-(2,6-dimethylphenyl)-1-piperazine-acetamide... 

A mixture of 800 g of potassium o-bromo-benzoate, 1,500 ml of bis-(2-methoxyethyl)ether, 355 g of N-ethyl-morpholine, 375 g of 2,3-dimethylaniline, and 30 g of cupric acetate is heated gradually with stirring to 140°C over a period of 90 minutes. The hot reaction mixture is then acidified with 260 ml of concentrated hydrochloric acid and the acidified mixture divided into 2 equal portions. One liter of water is added to each portion and the mixtures allowed to cool. The N-(2,3-dimethylphenyl)anthranllic acid which separates upon cooling is collected by filtration and recrystallized from bis(2-methoxyethyl)ether MP 229° to 230°C (corr.). 

Chemical Name N-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamide Common Name N-methylpipecolic acid 2,6-dimethylanilide... 

Chemical Name 2-[ [4-(1,1 -Dimethylethyl)-2,6-dimethylphenyl] methyl] -4,5-dihydro-1 H-imidazole hydrochloride... 

With regard to the resolution of enantiomers, some applications can be found with modified silica gel supports. Thus, a Pirkle-type CSP was used for the separation of 200 mg of a racemic benzodiazepinone [75]. Also tris-(3,5-dimethylphenyl)carba-mate of cellulose coated on silica [91, 92] was applied successfully to the resolution of the enantiomers of 2-phenoxypropionic acid and to oxprenolol, alprenolol, propranolol among other basic drugs. However, the low efficiency of this technique and the relative high price of the CSPs limits its use to the resolution of milligram range of sample. 

Silicon tetraisothiocyanate reaction with 2,6-dimethylamhne to yield 2,6 dimethylphenyl thiourea, 46, 70... 

A more effective control of both simple diastereoselectivity and induced stereoselectivity is provided by the titanium enolate generated in situ by transmetalation of deprotonated 2,6-dimethylphenyl propanoate with chloro(cyclopentadienyl)bis(l,2 5,6-di-0-isopropylidene-a-D-glucofuranos-3-0-yl)titanium. Reaction of this titanium enolate with aldehydes yields predominantly the. yyw-adducts (syn/anti 89 11 to 97 3). The chemical yields of the adducts are 24 87% while the n-u-products have 93 to 98% ee62. 

Dimethylphenyl piperazi-nium (DMPP) Synthetic Ganglionic... 

Arsine, 3-dimethylarsinopropylbis(but-3-enyI)-, 2, 1010 Arsine, dimethylphenyl-, 2,1006 Arsine, diphenylchloro-, 3,256 Arsine, diphenylcyano-, 3,256 Arsine, ethylenebis(dichloro-, 2,1005 Arsine, ethylenebis(dimethyl-. 2, 1006 Arsine, ethylenebis(diphenyl-, 2,1006 Arsine, ethylidynetris(methylenebisdimethyl-, 2, 1007 Arsine, ethylmethylphcnyl-complcxcs... 

Phosphine, (2-bromophenyl)dichloro-, 2,991 Phosphine, (w-chloroalkyl)dichloro-, 2, 991 Phosphine, chlorodimethyl-, 2, 991 Phosphine, chloro(dimethylamino)-, 2, 991 Phosphine, chlorodiphenyl-, 2, 990 Phosphine, cyclohexyl(o-anisyl)methyl-rhodium complexes asymmetric hydrogenation, 6, 251 Phosphine, [(dialkylphosphino)alkyl]diphenyl-, 2, 994 Phosphine, dichloromethyl-, 2, 991 Phosphine, dichlorophenyl-, 2, 990 Phosphine, diethylphenyl-, 2, 992 Phosphine, dimethyl-, 2,992 Phosphine, dimethylphenyl-, 2,992 Phosphine, diphenyl-, 2, 992 Phosphine, ethyldiphenyl-, 2, 992 Phosphine, ethylenebis(diethyl-, 2, 993 Phosphine, ethylenebis(diphenyl-, 2,993 Phosphine, ethylenebis(phenyl-, 2,992 Phosphine, ethylidynetris[methylene(diphenyl-, 2,994 Phosphine, [(ethylphenylphosphino)hexyl]diphenyl-, 2, 994... 

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