Dimethyl sulfoxide binding affinity

Later, the same group reported the synthesis of a more acidic 4,6-dinitrodibenzocyclo-butane-1,8-diol [8] and examined equilibrium constants for hydrogen bonding with various bases [9] (Table 9.1). Binding affinity of dinitro substituted bisphenol to TMP was 40-fold higher compared to that of unsubstituted one (run 1). Similar but moderate effects were observed with respect to other hydrogen acceptors, HMPA, 2,6-dimethyl-y-pyrone (DMP), tetramethylenesulfoxide (TMSO), and dimethyl sulfoxide (DMSO) (runs 2-5). Thus, the... 

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