4.4- Dimethyl-2-pentanol

Dimethyl-3-pentanoL DCC, DMAP, CH2CI2, 4 h. This group was developed as an improvement over the use of cylcohexanol for aspartic acid protection during peptide synthesis. ... 

Tab. 10.8 summarizes the application of rhodium-catalyzed allylic etherification to a variety of racemic secondary allylic carbonates, using the copper(I) alkoxide derived from 2,4-dimethyl-3-pentanol vide intro). Although the allyhc etherification is tolerant of linear alkyl substituents (entries 1-4), branched derivatives proved more challenging in terms of selectivity and turnover, the y-position being the first point at which branching does not appear to interfere with the substitution (entry 5). The allylic etherification also proved feasible for hydroxymethyl, alkene, and aryl substituents, albeit with lower selectivity (entries 6-9). This transformation is remarkably tolerant, given that the classical alkylation of a hindered metal alkoxide with a secondary alkyl halide would undoubtedly lead to elimination. Hence, regioselective rhodium-catalyzed allylic etherification with a secondary copper(l) alkoxide provides an important method for the synthesis of allylic ethers. 

Problem 13.39 Write a structural formula for a Grignard reagent and a carbonyl compound which react to give each of the following alcohols after hydrolysis (a) 2-butanol, (f>) benzyl alcohol, (c) 2,4-dimethyl-3-pentanol, (d) r-butanol. M... 

With the use of additives such as ammonia or 2,4-dimethyl-3-pentanol they managed to suppress dimer formation and observed complete amine racemization in 98% conversion. 

Heptanol, 2-methyl-3-hexanol, 2,4-dimethyl-3-pentanol, cyclo-pentanol, cyclohexanol, cyclo-heptanol, cyclooctanol, cis-and trans-2-methylcyclohexanol, cis- and trans-4-tert-butyl-cyclohexanol ai2o3 180-210 94... 

A total of 20 partition coefficients were measured using 1-pentanol, 2-methyl 2-hexanol, 2-methyl 3-hexanol, and 2,4-dimethyl 3-pentanol as the alcohols and C-6, C-8, C-10, C-12, and C-16 as the n-alkanes. For each alcohol, a 15-ml. aliquot of water with 1000 mg/L alcohol was placed in a 35 ml. vial with 15-ml. aliquot of NAPL and immediately sealed. The alcohol solutions were prepared quickly and immediately sealed with Teflon coated septa with no headspace to minimize volatilization. The samples were thoroughly shaken for 1 hour and allowed to separate for 24 hours. These mixing and separation times were sufficient for equilibration. Immediately following separation, the aqueous samples were analyzed for alcohol using a split injection Varian 3300 GC with FID detection. The partition coefficient was calculated by mass balance. 

C7H15N02 alpha-methyl-4-morpholineethanol 2109-66-2 457.71 39.836 2 12197 C7H160 2,4-dimethyl-3-pentanol 600-36-2 411.95 40.089 1.2... 

Novozym 435-catalyzed self condensation of isopropyl aleuriteate [46] at 90 °C in toluene and 2,4-dimethyl-3-pentanol as cosolvent gave the corresponding polyester in 43% yield (M = 5600). Subsequently, isopropyl aleuriteate was copolymerized with e-CL and random copolymers were obtained in around 70% yield with Mn values up to 10600. 

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