Dimethyl-1,1’-ferrocene

At this column temperature many of the compounds listed in Table 163 are separated. When a single component sample is handled, the column temperature should be 10 to 20°C lower than the indicated column temperature, (for example, ferrocene, ferrocenemercury chloride, iodoferrocene) or higher than the indicated temperature (namely 1,1 -diacetylferrocene, dimethyl 1,1 -ferrocene dicarboxylate, phenyl-ferrocene) but when the sample contains several ferrocenes the column temperature should be selected in order to optimize the separation. 

During the synthesis of 1,1 ferrocene dimethanol from ferrocene, the starting material, ferrocene and the intermediates, 1,1 -diacetyl-ferrocene and dimethyl 1,1 -ferrocene dicarboxylate all occur in the product, and chromatograms of this mixture are shown in Figure 234. 

FIGURE 6-6 Chemical stmcture of some common redox mediators (a) dimethyl ferrocene (b) tetrathiafidvalene (c) tetracyanoquinodimethane (cl) Meldola Blue. 

Fig. 7-71, Crystal structure of l,l -(l,4,10,13,-tetraoxa-7,16-diazacyclooctadecane-7,16-dimethyl)-ferrocene AgC104 (reproduced by permission of the American Chemical Society).

Substituted ferricenium tetrachloroferrates have been obtained photochemically from l.l -dimethyl-ferrocene and l.l -di-t-butyl-ferro-cene with CCI4 282> and from l.l -bis(triphenylsilyl)ferrocene with C5CI6... 

The kinetic behavior of the reductions of several Cu(II)N2S2 complexes, containing thioether/pyridyl chelate ligands, by ferrocene and l,r-dimethyl-ferrocene in acetonitrile points to the formation of a precursor complex prior to electron transfer.The rate constant for the oxidation of (hydroxyethyl)-ferrocene by [2-pyridyl(methylbis(2-ethyl)thioethyl)amine]copper(II) yields a [Cu(pmas)] self-exchange rate constant of 47 M s from the Marcus theory relation.The addition of NJ increases the rate of oxidation (F" and I" have no effect) by shifting the reduction potential upon the formation of [Cu(pmas)N3] and Cu(pmas)(N3)2 (NJ displacement of a thioether sulfur occurs in the latter species). The application of the Marcus relationship to the reductions of the [l,8-bis(2-pyridyl)-3,6-dithiaoctane]copper(II) complex by a series of Ru(II) ammine and bipyridyl complexes in 50% aqueous CH3OH yields a self-exchange rate constant of 0.63 s for the [Cu(pdto)] couple. " From the rate... 

Fig. 43 a-haloketone reduction with NADH model compound vs. dimethyl ferrocene [249, 250]... 

Gold 1,3 -dimethyl ferrocene ethylamine -0.1 1.76 Cytochrome C peroxidase was immobilized on a nylon membrane 17... 

Twelve quinone derivatives and three ferrocene derivatives were examined. Their cyclic voltammograms were measured with a film-coated GOD (0.5 Mg) CPE without mixed-in mediator immersed in the basal solution containing 1 mmol/dm mediator. However, for some mediators, such as tetra-methyl p-benzoquinone, 1,2-naphthoquinone, 1,4-naphthoquinone, ferrocene, and 1,1 -dimethyl-ferrocene a saturated solution (generally, of low solubility) was used. Figures 5 and 6 show the cyclic voltammograms of 2,6-dichoro-p-benzoquinone and BQ. The mid-point potential, Emid, was obtained from the cathodic and anodic peak potentials, Epc and Epa, respectively, by Emid (Epc+Epa)/2. All compounds examined were active as electron transfer mediators for bioelectrocatalysis with the GOD CPEs with mixed-in mediator (usually mn = 5%), except tetramethyl-p-benzoquinone (that is. 

Ferrocene-1,1 -dicarhoxylic acid [1293-87-4] M 274.1, m >250°(dec), >300°. Orange-yellow crystals from AcOH. Sublimes above 230°. Monomethyl ester m 147-149° [Dokl Acad Nauk USSSR 115, 518 1957]. Dimethyl ester m 114-115° [J Am Chem Soc 14, 3458 1958]. Diacid chloride m 92-93° from pet ether. [Dokl Acad Nauk SSSR 120 1267 1958 127 333 7959.]... 

Harrowfield et al. [37-39] have described the structures of several dimethyl sulfoxide adducts of homo bimetallic complexes of rare earth metal cations with p-/e rt-butyl calix[8]arene and i /i-ferrocene derivatives of bridged calix[4]arenes. Ludwing et al. [40] described the solvent extraction behavior of three calixarene-type cyclophanes toward trivalent lanthanides La (Ln = La, Nd, Eu, Er, and Yb). By using p-tert-huty ca-lix[6Jarene hexacarboxylic acid, the lanthanides were extracted from the aqueous phase at pH 2-3.5. The ex-tractability is Nb, Eu > La > Er > Yb. 

Initial protonation of iron in protodesilylation of trimethylsilylferrocene was not, however, favoured as a mechanism by Marr and Webster689, who measured rates by the spectroscopic method using hydrochloric acid in 20 vol. % aqueous methanol (Table 235) and found that the rate of desilylation of the ferrocene compound was little more than that for the 4-methoxyphenyl and 2,4-dimethyl compounds. The similarity of the spread of rates in the different media and the similar activation energies and entropies were considered as evidence that the transition states for reaction of all three compounds were similar. The lower activation energy obtained for the 4-methoxyphenyl relative to the ferrocene compound may arise from the different media involved the difference in entropy seems, however, to be rather larger than one might have expected even allowing for the solvent differences. 

Ferrocene, reaction with bis(dimethyl-amino) methane to yield di-methylaminomethylferrocene, 40,31... 

Togni and co-workers have used the convergent methodology to link phosphine-containing chiral ferrocene ligands on the cyclophosphazene core to obtain dendrimeric structures of the type 37 (Fig. 21) (201). The reaction with the cyclophosphazene end occurs by the replacement of the P-Cl bond and by the formation of the P-0 bond. The dendrimers contain twelve and sixteen ferrocene moieties respectively. The phosphine units present can coordinate to Rh(I) to afford metallic dendrimers, which have been shown to be excellent catalysts for the enantioselective hydrogenation of dimethyl itaconate. The product... 

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