5-Dimethyl-aminonaphthalene

Another redox switchable system is based on dyad 21 in which 2-chloro-1,4-naphthoquinone is covalently attached to 5-dimethyl-aminonaphthalene via a non-conjugated spacer. The intrinsic fluorescence of the dansyl excited state in dyad 21 is strongly quenched, due to the intramolecular electron transfer from the excited dansyl to the adjacent quinone acceptor. However, the fluorescence can be switched on by addition of a reducing agent. Apart from chemical switching, the fluorescence of dyad 21 can also be switched electrochemically. This can be realized using a photoelec -trochemical cell, and the solution starts to fluoresce upon application of a reductive potential.31... 

SYNS 1 -CHLOROSULFONYL-5-DIMETHYL-AMINONAPHTHALENE DANSYL DANSYL CHLORIDE DIMETHYLAMINONAPHTHALENE-SULFONYL CHLORIDE 1-DIMETHYLAAIINO-NAPHTHALENE-5-SULFONYL CHLORIDE 1-piMETHYXAMINO)-5-NAPHTHALENESULFONYL-CHLORIDE 5-DIMETHYLAMINONAPHTHYL-5-SL LFONYL CHLORIDE... 

Sodium a-(N,N-dunethylammo)naphthalenide (1). The radical anion is prepared and used in the same way as sodium naphthalenide. However the derived a-dimethyl-aminonaphthalene can be separated from products simply by an aqueous wash.1... 

From a theoretical point of view this is an extremely interesting reaction. The displacement of a hydroxyl group from a saturated carbon atom appears to be unknown in basic solution. The fact that amino-methane sulfonic acid can be isolated from the bisulfite addition product of formaldehyde on treatment with ammonia does not prove, of course, that a direct displacement, such as is indicated in XVI to XVII, actually occurred. Furthermore, it is quite clear that preliminary formation of an imine (XVIII) is not necessary for the reaction of aromatic amines with sodium bisulfite (steps XIX to XVIII to XVII, etc.). 1-Dimethyl-aminonaphthalene-4-sulfonic acid (XX) and l-aminonaphthalene-4-sulfonic acid (XIX) show similar reaction kinetics 16a when treated with sodium bisulfite, yet with the tertiary amine (XX) it is not possible to write an imino structure corresponding to XVIII. 

Aldehydes, reducing sugars, ketones Dansyl hydrazide-1-dimethyl aminonaphthalene-5-sulfonyl hydrazide... 

Fluorescence spectroscopy is another powerful technique that can be utilized to study protein conformation in solution. Fluorescent probes like TNS [6-(p-toluidino)naphthalene-2-sulfonic acid], a hydro-phobic probe, and a sulfhydryl probe such as acry-lodan [6-(acryloyl-2-dimethyl aminonaphthalene] are useful for studying protein conformation. Twelve-kDa... 

The generation of organolithium reagents by o-lithiation of alkyl phenyl ethers, dialkylaminobenzenes, and benzyldialkylamines followed by their reaction with halogenophosphines has afforded a range of new substituted arylphosphines, e.g., (10) and the chiral phosphine (11). Directed-lithiation of 1-dimethyl-aminonaphthalene, followed by treatment with chlorodiphenylphosphine, affords a more direct route to the phosphine (4). The diphosphines (12) are formed in the reactions of chlorodiethylphosphine with u-lithio lithium phenolate... 

Amino-sugars have been detected in the pmol range after condensation with 2-phthalaldehyde in the presence of 2-mercaptoethanol. Amino-acids also react yielding fluorescence intensities similar to those of amino-sugars. The products of acid hydrolysis of glycoproteins have been treated with 1-dimethyl-aminonaphthalene 5-sulphonyl chloride (dansyl chloride). The dansyl amino-... 

Detection may be facilitated by preparation of colored or, more often, fluorescent derivatives prior to spotting and development. Examples include dansylation (reaction with 1-dimethyl aminonaphthalene-5-sulfonyl chloride) of amino acids and formation of 2,5-dinitrophenylhydrazones of amino acids and ketosteroids. Other reactions that have been used include oxidation, reduction, hydrolysis, ha-logenation, enzymatic, nitration, diazotization, esterification, and etherification (Szepesi and Nyiredy, 1996 Kovar and Morlock, 1996). Prechromatographic derivatization sometimes improves separation, stability, and/or quantification of the analytes in addition to providing visualization. 

The dependence of the photoionization process of anilines in aqueous solution on pH could be illustrated by the case of A,lV-dimethyl-l-aminonaphthalene (2b)112. The... 

Selenium has been determined with 5,5-dimethyl-1,3-cyclohexanedione [51], 6-amino-1-hydroxynaphthalenesulphonic acid [52,53], and l-aminonaphthalene-7-sulphonic acid [54], Determinations of Se involved also the following dyes Rhodamine B [55], Methylene Blue [56], Xylenol Orange [57], and Rhodamine 6G (by the amplification method, in iodide medium, after oxidation of iodide to iodine, and reaction of the I03 with the dye) [58]. 

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