Dilated lateral ventricles

Possible abnormalities that can be observed include microphthalmia/anophthalmia, retinal fold, dilated lateral ventricles, and hemorrhages affecting the brain. 

Mouse (C3H/HeN) once Gd 13, 14, 15, 16 (GW) 16 (decreased survival of offspring impaired righting response gait and hindlimb crossing decreased brain weight dilated lateral ventricles smaller caudate putamen) Inouye et al. 1985 MMC... 

Mass effect is detected in a relatively high percentage of nonhemorrhagic cases (44%, Miyasaka et al. 1997). Cortical sulci obliteration and lateral ventricle displacement are frequently observed. Mass effect could be related to the size of the AVM itself or to the presence of large dilated venous sacs or ectatic veins. White-matter edema is rarely the cause of mass effect. 

Flg.5.13. CT reveals massive basal subarachnoid hemorrhage and dilated temporal horns of the lateral ventricles... 

Studies Blood connt, chemistry, and vitamin levels were normal. Syphilis test was negative. Brain MRI revealed a communicating hydrocephalus, with dilated frontal and temporal horns of the lateral ventricles, and slight-moderate periventricnlar white matter enhancement on contrast. No obstruction or focal mass was evident. 

Atrophy of the optic nerve appears to be a consistent finding. Pigmented macular protrusions have been observed by Hagbbrg et al. (1965). The spinal fiuid was found to be clear and colorless (Brown et al. 1954), and cells were not increased. Spinal fiuid protein was initially elevated (480 mg%) and later normal (51.3 mg%) in the case of Hagberg et al. The electroencephalogram in this patient showed lack of the normal basal rythmic activity and cortical activity. Ventriculography revealed marked dilatation of the ventricles with paper-thin walls and signs of underdevelopment of the cerebellum. Routine laboratory examinations were normal. Vacuolized lymphocytes were not seen. 

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