Dicaffeoyl tartaric acid

The roots of . purpurea do not contain echinacoside, but cichoric acid (2 ,3 -dicaffeoyl tartaric acid) and caftaric acid (monocaffeoyl tartaric acid) as shown in Figures 4 and 11. Cichoric acid was first found as a major constituent in the aerial parts of Echinacea species [82, 83]. Later it was found that it is abundant also in Echinacea purpurea roots and the content has been determined by HPLC to be 0.6-2.1% [84]. Schenk and Franke recently found 0.9% in cultivated material [15]. Cichoric acid undergoes rapid enzymatic degradation (see Echinacea purpurea aerial parts, section on caffeic acid derivatives and phenolic acids) [84]. Therefore, the quality of phytopreparations needs to be thoroughly checked. For analytical methods, see also Echinacea purpurea aerial parts. 

The main caffeic acid derivative in the aerial parts of Echinacea purpurea is cichor-ic acid (2R,3R-0-dicaffeoyl-tartaric acid). It was first isolated from the leaves of . purpurea by Becker and Hsieh [83]. Hsieh [106] reported no data on the optical activity of cichoric acid. The cichoric acid isolated later from . purpurea by Remiger [84] and by Soicke et al. [107] had an optical rotation [a] of ca. -370 . In contrast, the cichoric acid first isolated by Scarpati and Oriente [108] from Cichorium intybus displayed a rotation of +383.5 . Cichoric acid from lettuce Lac-tuca sativa) [109] and from endives (Cichorium endivia) [110] was also dextrorotatory. Synthetic studies by Scarpati and Oriente [108] showed that cichoric acid from Cichorium intybus contains a residue of (2S,3S)-(-)-tartaric acid. Conversely, that in... 

The herb (leaves, flowers, shoots, etc.) contains inulin, fructose, choline, resin, chi-coric acid (dicaffeoyl tartaric acid), esculetin, esculin (esculetin-6-glucoside), cichoriin, and others (list and horhammer). ... 

Dicaffeoyl-D-tartaric acid (Chicoric acid) Onychium japonicum Kze. C22H18O12 204 206 371 54... 

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