Diazoxide diabetes with

VASODILATOR ANTIHYPERTENSIVES CORTICOSTEROIDS Risk of hyperglycaemia when diazoxide is co administered with corticosteroids Additive effect both drugs have a hyperglycaemic effect Monitor blood glucose closely, particularly with diabetes... 

Diazoxide is a potent vasodilator chemically resembling the thiazides, but it is not a diuretic. Diazoxide can be administered both parenterally and orally. Caution has been stressed when diazoxide is administered as an intravenous bolus into the pulmonary artery because the solution is highly alkaline (pH 11.6) and irritating to vascular tissue (Cotter and Honey, 1980). In one study with chronic oral diazoxide administration (300-600 mg/day), five of seven patients had important side effects including diabetes mellitus, fluid retention, nausea, vomiting, and postural hypertension that required discontinuation of the drug (Wise, 1983). 

---