Diastereomers drawing

There are eight diastereomers of 1,2,3,4,5,6-hexachlorocyclohexane. Draw each in its more stable chair conformation. One isomer loses HC1 in an E2 reaction nearly 1000 times more slowly than the others. Which isomer reacts so slowly, and why ... 

To start the polymerisation the X atoms in Fig 10.13 are replaced by a growing alkyl chain and a co-ordinating propene molecule. Co-ordination of propene introduces a second chiral element and several diastereomers can be envisaged. The step-by-step regulation of the stereochemistry by the site can be most clearly depicted by drawing the molecule as shown in Figure 10.14, a... 

Identify the relationship in each of the following pairs. Do the drawings represent constitutional isomers or stereoisomers, or are they just different ways of drawing the same compound If they are stereoisomers, are they enantiomers or diastereomers (Molecular models may prove useful in this problem.)... 

A-l. For each of the following pairs of drawings, identify the molecules as chiral or achiral and tell whether each pair represents molecules that are enantiomers, diastereomers, or identical. 

Epoxyphospholanes 105 are directly prepared from 2-phospholenes 94. Epoxidation of 94 with sodium peroxide give a single diastereomer of erythro 105E (X-ray analysis gives the ORTEP drawing in Fig. 10) in stereospecific and stereoselective manner (Scheme 34 and Table 6). However, 2,3-epoxidation of... 

Draw all the stereoisomers of 2-bromo-3-chloiobutane and indicate whether they are enantiomers or diastereomers. 

Draw all the distinct stereoisomers for each structure. Show the relationships (enantiomers, diastereomers, etc.) between the isomers. Label any meso isomers, and draw any mirror planes of symmetry. 

When the first compound shown here is treated with sodium methoxide, the only elimination product is the trans isomer. The second diastereomer (blue) gives only the cis product. Use your models and careful drawings of the transition states to explain these results. 

Solved Problem 7-4 showed that the debromination of (i ,i )-2,3-dibromobutane gives als-but-2-ene. Draw the same reaction using the (S,S) enantiomer and show that it gives the same diastereomer of the product. 

Problem 5.18 Draw all the possible stereoisomers for each compound and label pairs of enantiomers and diastereomers (a) CH3CH(OH)CH(OH)CH3i (b) CH3CH(OH)CH(CI)CH3. 

Problem 5.19 Draw the enantiomer and one diastereomer for each compound. 

Problem 5.22 Without drawing out the structures, label each pair of compounds as enantiomers or diastereomers. 

To draw all possible stereoisomers, remember that a disubstituted cycloalkane can have two substituents on the same side of the ring (ds isomer, labeled A) or on opposite sides of the ring (trans isomer, labeled B). These compounds are stereoisomers but not mirror images of each other, making them diastereomers. A and B are two of the four possible stereoisomers. 

Problem 5.25 Draw all possible stereoisomers for each compound. Label pairs of enantiomers and diastereomers. 

An acid-base reaction of (R)-sec-butylamine with a racemic mixture of 2-phenylpropanoic acid forms two products having different melting points and somewhat different solubilities. Draw the structure of these two products. Assign R and S to any stereogenic centers in the products. How are the two products related Choose from enantiomers, diastereomers, constitutional isomers, or not isomers. 

Problem 8.18 Given that an E2 reaction proceeds with anti periplanar stereochemistry, draw the products of each elimination. The alkyl halides in (a) and (b) are diastereomers of each other. How are the products of these two reactions related ... 

Draw all isomers of molecular formula CaHgBrCI. Label pairs of diastereomers and constitutionai isomers. 

Problem 10.1 Draw the six alkenes of molecular formula C5H10. Label one pair of diastereomers. 

Problem 29.15 Draw the enantiomer and any two diastereomers of cholesterol. Does the OH group of cholesterol occupy an axial or equatorial position ... 

Problem 4.12 Draw stereochemical formulas for all the possible stereoisomers of the following compounds. Label pairs of enantiomers, and meso compounds. Tell which isomers, if separated from all other stereoisomers, will be optically active. Pick out several examples of diastereomers. 

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