Diamox Sodium

Diamonds Sapphires Diamond synthesis Diamomque Diamoni quell Diamomquelll Diamomte Diamontina Diamox Diamox sodium Diampron [3671-72-5]... 

Proprietary Name. Diamox Sodium C4HsN4Na03S2 = 244.2 CAS—1424-27-7 Soluble in water. 

The following abbreviations will be used ADH—alcohol dehydrogenase DPN — diphosphopyridine nucleotide DPNH—reduced diphosphopyridine nucleotide OP—1,10-phenanthroline 8-OHQ—8-hydroxyquinoline a,a -D—a,a -dipyridyl 8-OHQ5SA—8-hydroxyquinoline-5-sulfonie acid TU—thiourea EDTA—ethylene-diamine tetraacetic acid zincon —2-carboxy-2 -hydroxy-5-sulformazylbenzene diamox — sodium 2 - acetylamino -1,3,4- thiodiazole - 5 - sulf onamide NaDDC — so -dium-diethyldithiocarbamate CGP—carbobenzoxyglycyl-L-phenylalanine. 

Acetamide, Acetazolamide Sodium, AK-Zol, Albox, AK-Zol, Dehydratin, Diamox, Diamox Sequels, Diamox Sodium, Ederen, Glauconox, Glaupax, Inidrase, Ledamox, Nephramid, Ocu-zolamide, Oratrol, Storzolamide)... 

It could be shown, moreover, (Vallee and Neurath, 1955) that five times recrystallized carboxypeptidase was completely inhibited by metal chelating agents, such as 8-OHQ-5SA and 1-10 phenthroline at concentrations of 10 W,Q ,Q Dat concentrations of 10" Af, and some 30% byEDTA at 10 M. These are all known to form complexes with zinc in simple systems. In these experiments, the buffered enzyme solutions were incubated with the chelating agent at pH 7.5, 4°C., for 1 hour prior to the addition of the substrate. Inhibition did not occur when these chelating agents were first incubated with an equimolar amount of zinc, cupric, or ferrous ions. Sodium diethyldithiocarbamate, zincon, sulfanilamide, and diamox, the latter two employed because of their effect on carbonic anhydrase, had little, if any, effect on carboxypeptidase activity. DPN, nicotinamide, and A-methylnicotinamide, examined because of their effect on the ADH sys-... 

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