Dexedrine. See

The amphetamines, such as amphetamine, dextroamphetamine (Dexedrine), and metliainphetainine (Desoxyn), are sympatiiomimetic (ie, adrenergic) dru that stimulate the CNS (see Chap. 22). Their drug action results in an elevation of blood pressure, wakefulness, and an increase or decrease in pulse rate The ability of these drugs to act as anorexiants and suppress the appetite is thought to be due to their action on the appetite center in the hypothalamus. 

Compared to the 2- hour duration of the subjective effects of natural marijuana, the effects of a mixture of the eight isomers of this synthetic derivative lasted much longer - up to 30 hours. We gave some Dexedrine to the above subject to see if it would reduce or shorten his symptoms. Not surprisingly, his alertness improved but all the other effects persisted unchanged. 

Many psychomotor stimulants possess activities similar to those of amphetamine and have been discussed previously (see Chapter 10). Of primary importance to our discussion of the psychomotor stimulants are amphetamine Adderall, Benzedrine, Dexedrine), methampheta-mine (Desoxyn), and methylphenidate (Concerta, Ritalin, Metadate, Methylin). 

On the maiden flight of the shuttle in April, rookie astronaut Robert Crippen avoided the queasies by dipping into the medical kit for a NASA-developed prescription of Dexedrine, a stimulant, and scopolamine, a tranquilizer. (Rogers 1981 see Appendix A)... 

Dextroamphetamine (dexedrine, others), with greater CNS action and less peripheral action, is FDA approved for the treatment of narcolepsy and attention-deficit/hyperactivity disorder (see below). 

This study investigated the efficacy of using dextroamphetamine (Dexedrine ) as a countermeasure to deep loss during sustained operations in which it is impossible for persotmel to gain any restorative sleep for up to 40 hours. Although, previously published reports have proven that amphetamines are effective for enhancing performance and alertness (see Caldwell et al., 1994, for a review there had been no controlled aviation studies. However, there was evidence that amphetamines would effectively counter sleep loss and fotigue in aviation personnel. 

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