Dexamethasone edema

Dexamethasone Hyperglycemia, edema, adrenal cortical insufficiency Dose given orally once daily... 

Dexamethasone 8 mg P0 BID for 8 doses—start day prior to chemo (decreases lower extremity edema)... 

Dexamethasone Testing of adrenal cortical hyperfunction cerebral edema associated with primary or metastatic brain tumor, craniotomy, or head injury. Tnamc/no/one Treatment of pulmonary emphysema where bronchospasm or bronchial edema plays a significant role, and diffuse interstitial pulmonary fibrosis (Hamman-Rich syndrome) in conjunction with diuretic agents to induce a diuresis in refractory CHF and in cirrhosis of the liver with refractory ascites and for postoperative dental inflammatory reactions. 

Thyroid 1 uptake may be decreased. False-negative results with the nitroblue-tetrazolium test for bacterial infection. Dexamethasone, given for cerebral edema, may alter the results of a brain scan (decreased uptake of radioactive material). 

Neurologic disorders Cerebral edema (large doses of dexamethasone are given to patients following brain surgery to minimize cerebral edema in the postoperative period), multiple sclerosis... 

Tobramycin Dexamethasone Ophthalmic (TobraDex) [Antibiotic/Anti-inflammatory] Uses Ocular bacterial Infxns associated w/ significant inflammation Action Antibiotic w/ anti-inflammatory Dose Oint soln Caution [C, M] Contra Aminoglycoside sensitivity Disp Oint susp 2.5, 5, 10 mL tobramycin 0.3% dexamethasone 0.1% SE Local irrita-tion/edema see Tobramycin EMS See Tobramycin OD Unlikely w/ ophthalmic form... 

For parenteral administration in intensive therapy or in emergendes, the sodium phosphate ester may be given intravenously by injection or infusion, or intramuscularly by injection. Dexamethasone sodium phosphate is also used in the treatment of cerebral edema caused by malignancy. The sodium phosphate ester is given by intra-articular, intra-lesional or soft tissue injection. Dexamethasone acetate may be given by intramuscular injection in conditions where corticosteroid treatment is indicated, but a prompt response of short duration is not required. 

Posurdex Dexamethasone implant Allergan Phase 111 Diabetic macular edema Biodegradable intravitreal rod-shaped implants... 

A 60-year-old smoker was treated with interferon alfa (100 MU/week for 2 months and 9 MU/week for 15 weeks) for cutaneous melanoma. Ocular examination was normal before treatment, but he developed acute loss of peripheral vision in his left eye after 23 weeks. Examination was consistent with anterior ischemic optic neuropathy, and there was optic disc edema, a pupillary defect, and circular visual field constriction in the left eye. There was renal artery constriction in both eyes. Despite treatment with aspirin, high-dose dexamethasone, heparin, and finally withdrawal of interferon alfa, loss of visual function progressed and affected both eyes. Ciclosporin was started, but he was considered to have irreversible loss of visual function. 

An 81-year-old man underwent CT scanning of the head with intravenous contrast enhancement (100 ml of the non-ionic contrast medium iopamidol). After the injection he complained of sweating and nausea and had a cardiorespiratory arrest. Immediate resuscitation and intravenous dexamethasone and adrenaline were not successful. Mast cell tryptase activity in a sample taken 4 hours after death was high. At autopsy, the coronary and pulmonary arteries were patent. The right heart chambers were moderately enlarged. The lungs were hyperemic and edematous and there was obstructive edema of the larynx. 

A 66-year-old man with neurocysticercosis treated with glucocorticoids and praziquantel developed headache and confusion. He did not have a ventricular shunt inserted. A contrast-enhanced CT scan showed multiple focal enhancing lesions with mild edema. An MRI scan of the head was reported as being most consistent with neurocysticercosis. He was given dexamethasone 2 mg bd and praziquantel 50 mg/kg/day. A few days later his headache worsened, with nausea and drowsiness. After 2 weeks he became stuporose and had to be ventilated. A CT scan showed multiple areas of deep subcortical focal edema near the areas of previously enhancing cysts, a striatocapsular stroke, and obstructive hydrocephalus. Two weeks after the last dose of praziquantel and despite a ventriculostomy tube he died. 

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