Detergents inhibitor action

Corrosion Inhibitors. The corrosion inhibitors used in diesel fuel ate generally similar to those used in gasoline and, like the latter, produce an effect primarily by surface action. If amine additives ate used for detergency, these may provide some corrosion protection as well. 

Acetylcholinesterase is subject to substrate Inhibition at high concentrations, but Mlchaells kinetics are observed at lower concentrations, because the substrate constant and the Mlchaells constant differ by a factor of 100. Turnover numbers run about 2-9 x 10 min l, and (Mlchaells constant) values are about 0.2 mM.76,116 Whatever the source, the enzyme is subject to inhibition by the same reversible and irreversible inhibitors. Most of the kinetic work has been done with the saline-extracted 11S enzyme from electric eel and the detergent-extracted 6S enzyme from erythrocytes. The former Is a tetramer derived from the native enzyme by the action of proteases the latter is a dimer. 

Modifying Effects of Detergents on the Action of Inhibitors, in Vitro... 

Some saponins from plants are quite phytotoxic,36 but little is known of their mode(s) of action. Some of these compounds have effects on membrane properties, due to their detergent-like activity. However, all membrane effects are apparently not due to nonspecific effects on membrane lipids. Kauss and Jeblick23 provided indirect evidence that digitonin effects on plant cell Ca2+ uptake are due to effects on membrane protein phosphorylation/dephosphorylation processes. Betulin (Fig. 10.1), a phytotoxic saponin,22 is known for its pharmaceutical activity. It is an inhibitor of DNA topoisomerase.45 The natural product-based DNA topoisomerase inhibitor drug podophyllotoxin is also phytotoxic.37... 

By such an adsorption of 3 at the membrane it is intended to prevent an establishment of cancer cells in the healthy tissue. A somewhat different interpretation of the action of such detergents has been given by Calvin (31), who supposes that the enzymes are extracted from the cell membrane by the formation of detergent micels or that inhibitors are stabilized in such away that they cannot interact anymore with the enzyme. 

Applications. a-Sulfo methyl ester surfactants deriving from Qe—Cig fatty acid (e.g., ASMT, the tallowate) are appropriate for use in phosphate-free laundry detergents they have, however, a tendency to generate too much foam in European drum machines when the washing liquid is subjected to extensive mechanical action. The addition of an effective foam inhibitor or soaps can correct this drawback. ASME is also used in the formulation of syndet bars (laundry bars based on synthetic surfactants). 

Uses Corrosion/scaie inhibitor for use in high fluid level wells which have high water-to-oii ratio prevents deposition of min. scales exhibits detergent action which produces desirable system cleanup Regulatory SARA reportable... 

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