Trihexyphenidyl Desipramine

Clinically important, potentially hazardous interactions with abacavir, clidinium, clomipramine, desipramine, dicyclomine, digoxin, doxepin, flavoxate, glycopyrrolate, hyoscyamine, imipramine, mepenzolate, methantheline, nortriptyline, oxybutynin, procydidine, propantheline, protriptyline, scopolamine, trihexyphenidyl, trimipramine... 

Simultaneous amitriptyline, amoxapine, benztropine, brompheniramine, chlorpheniramine, chlorpromazine, clomipramine, cyproheptadine, desipramine, dothiepin, doxepin, fluoxetine, haloperidol, imipramine, loxapine, maprotiline, meperidine, mesoridazine, methadone, metoclopramide, mianserin, moclobemide, nomifensine, nordoxepin, norfluox-etine, norpropoxyphene, northiaden, pentobarbital, pheniramine, promethazine, propoxyphene, propranolol, protriptyline, quinidine, quinine, sulforidazine, thioridazine, thiothixene, tranylcypromine, trazodone, trihexyphenidyl, trimipramine, triprolidine... 

In a double-blind study 3 patients given a phenothiazine and benzatropine for the parkinsonian adverse effects, developed an intermittent toxic confusional state (marked disturbance of short-term memory, impaired attention, disorientation, anxiety, visual and auditory hallucinations) with peripheral antimusearinies signs. Similar reactions occurred in 3 elderly patients given imipramine or desipramine, with trihexyphenidyl, and in another man given chlorpromazine, benzatropine and doxepin. ... 

---