Designed recognition

For example, in Figure 3 it is demonstrated that tetrahydrofuran (THF) and formamlde can be mixed AO 60 to establish a cosolvent as designated. Recognition of this fact makes it possible to explore a number of casting solutions which, because they contain a volatile component, do not require the difficult evaporation procedures discussed above. In addition, it is possible to explore a number of non-classical or novel casting solutions as will be demonstrated below. 

The aromatic Ti-electron system of TCDD was targeted through non-covalent interactions with several aromatic comonomers capable of forming n-n interactions with the template at the stage of polymerisation. In particular, the electron deficient 2,3,4,5,6-pentafluorostyrene (8) and the electron rich l,4-bis-(3/4-vinylbenzoxy)-benzene (9) and l-methoxy-3,5-bis-(4-vinylbenzyloxy)-benzene (10) were used (Fig. 7.4). As a consequence of the template structure and the expected n n complex between the diurea template and the monomer, the designed recognition site should be equipped with two aromatic amino groups situated on both sides of the... 

L-Configuration if not otherwise designated. Recognition threshold value in mmol/1. 

Center for Molecular Design Recognition, Department of Chemistry, University of South Florida, Tampa, Florida 33620 USA... 

I-J and G Klebe 1996. What Can We Learn From Molecular Recognition in Protein-Ligand nplexes for the Design of New Drugs Angewandte Chemie Iniemational Edition in English 2588-2614. 

There are three advantages to study molecular recognition on surfaces and interfaces (monolayers, films, membranes or soHds) (175) (/) rigid receptor sites can be designed (2) the synthetic chemistry may be simplified (J) the surface can be attached to transducers which makes analysis easier and may transform the molecular recognition interface to a chemical sensor. And, which is also a typical fact, this kind of molecular recognition involves outside directed interaction sites, ie, exo-receptor function (9) (see Fig. 5b). 

E. Weber, ed., Supramolecular Chemisty II—Host Design and Molecular Recognition, Top. Curr. Chem., Vol. 175, Springer, Bedin-Heidelberg, 1995. 

G. Van Binst, ed.. Design and Synthesis of Organic Molecules Rased on Molecular Recognition, Springer, New York, 1986. 

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