Receptors, rigid

There are three advantages to study molecular recognition on surfaces and interfaces (monolayers, films, membranes or soHds) (175) (/) rigid receptor sites can be designed (2) the synthetic chemistry may be simplified (J) the surface can be attached to transducers which makes analysis easier and may transform the molecular recognition interface to a chemical sensor. And, which is also a typical fact, this kind of molecular recognition involves outside directed interaction sites, ie, exo-receptor function (9) (see Fig. 5b). 

A. M. Davis and S. J. Teague, Hydrogen bonding, hydrophobic interactions, and failure of the rigid receptor hypothesis, Angew. Chem. Int. Ed. 38 736 (1999). 

There are three advantages to study molecular recognition on surfaces and interfaces monolayers, films, membranes nr solids) (/ ) rigid receptor sites... 

Schopohl MC, Faust A, Mirk D, Frohlich R, Kataeva O, Waldvogel SR (2005) Synthesis of rigid receptors based on triphenylene ketals. Eur J Org Chem 14 2987-2999... 

Hydrophobic Interactions, and Failure of the Rigid Receptor Hypothesis. 

In this theory, it is assumed that there is a rigid receptor site and that morphine and its analogues fit into the site in a classic lock-and-key analogy. 

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