Design scenarios

Constant Flow into Protected Equipment For the steady-state design scenario with a constant, steady flow of fluid from a pressure source that is above the maximum aUowed pressure in the protected equipment, volume is being generated within the equipment at a rate RV = F/ f. Substituting into Eq. (26-21) and noting that the specific volume of the vent stream is l/p, gives the required mass flow rate ... 

It is important to note that the worst case should be something that is reahstic, not something that is conceivable but extremely unlikely. The Dow Chemical Company has adopted the following philosophy for design scenarios in terms of independent causative effects ... 

Scenarios that require the coincident occurrence of two or more totally independent events are not credible design scenarios. 

It can be user-friendly because of its effective graphical simulation interface and its flexibility, which facilitates users to design scenarios for target regions and... 

For steady-state design scenarios, the required vent rate, once determined, provides the capacity information needed to properly size the relief device and associated piping. For situations that are transient (e.g., two-phase venting of a runaway reactor), the required vent rate would require the simultaneous solution of the applicable material and energy balances on the equipment together with the in-vessel hydrodynamic model. Special cases yielding simplified solutions are given below. For clarity, nonreactive systems and reactive systems are presented separately. 

In fact, the above design scenario requires very low overall pass conversions to achieve significant reductions in the standing hypochlorite concentrations. It is... 

The two-component 2-aminothiazole library shown in Fig. 1 is used to illustrate different library design scenarios using the SELECT and MoSELECT programs. 

Future development efforts in field study design and data management should 1) develop methodologies for choosing sampler location, sampling schedule, and sampling devices 2) measure the collection efficiency of available samplers as a function of particle size, windspeed and wind direction 3) create a series of "typical" design scenarios which can be specified for different aerosol study objectives 4) develop standardized data bases from which ambient and source information can be recovered. 

There are a few key design scenarios commonly requested by medicinal chemists. They are described in the following sections. 

This is the standard library design scenario which is supported by most in-house and commercial vendor tools. The user-defined reaction is usually a Markush reaction drawing commonly in the format of MDL ISIS sketch or. rxn file (35). Chemists may also supply reactant sets for each reaction component either by loading pre-defined sets of molecules or by retrieving them via searches into chemical reactant databases. Molecular property calculations and analysis on the reactants are performed, and selections are made based on these results. This is commonly known... 

Using the same set of software capabilities, PGVL Hub also supports other design scenarios such as Singleton Design that is commonly practiced by medicinal chemists, Markush Exemplification where the reaction scheme becomes a Markush core structure, and reactant sets become R-group sets, and Lead Centric Mining (29). 

Dow has adopted the following philosophy for design scenarios in terms of independent causative effects ... 

Metamodels have been widely used in many fields of engineering, to replace rigorous mathematical models when they become too time-consuming or prone to numerical problems. One of the most typical uses of metamodels has been in optimal design where many design scenarios can be easily analysed by optimisation techniques. 

Satoh, K., and Yang, K.T. (2000) A Horizontal Fire-Whirl Design Scenario for Engineering Performance-Based Fire-Code Applications, Int. Journal on Engineering Performance-Based Fire Codes. Vol. 2, No. 2,48-57. 

The benefits of the direct process support have been validated on the basis of the Polyamide-6 conceptual design scenario used in the IMPROVE project (cf. Sect. 1.2). In the following, we briefly deal with three parts of the overall scenario. 

To this aim, the current development situation is analyzed via the product state of several source databases or tools. The scenario shown here is a simplification of a part of the design scenario described in Subsect. 1.2.2. Here, the selection and adaption of a mathematical model is treated, to simulate the separation of the final product Polyamide-6 from the residue monomer Caprolactam. 

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