Depression tianeptine

Maprotiline, Moclobemide, Mianserin, Fluoxetine (Prozac), Paroxetine, Sertraline, Fluvoxamine, Citalopram, Venlafaxin (generic IR formulation and the brand Venlafaxine XR), Mirtazapine, Flupentixol-melitracen (Deanxit), Tianeptine, Extract of St. John s Wort, Buspirone Depression and anxiety... 

Wagstaff, Antona J., Douglas Ormrod and Caroline M. Spencer, Tianeptine A Review of Its Use in Depressive Disorders , CNS Drugs 15, no. 231-59 (2001)... 

The behavioural effects of two antidepressants with opposite molecular actions, ie. tianeptine (a serotonin reuptake enhancer) and fluoxetine (a serotonin reuptake blocker) have been assessed and it was concluded that, apart from the effects on serotonin reuptake, these dmgs have other mechanisms playing an important role in the anti-depressant action <00AF5>. 

Chamba G, Lemoine P, Flachaire E, et al Increased serotonin platelet uptake after tianeptine administration in depressed patients. Biol Psychiatry 30 609-617, 1991... 

Guelfi JD, Pichot P, Dreyfus JF Efficacy of tianeptine in anxious depressed patients results of a multi-center trial versus amitriptyline. Neuropsychobiology 22 41-48, 1989... 

London E, Fanelh RJ, Kimes A, et al Effects of chronic nicotine on cerebral glucose utilization in the rat. Brain Res 520 208-214, 1990 Lonnqvist J, Sihvo S, Syvalahti E, et al Moclobemide and fluoxetine in atypical depression a double-blind trial. J Affect Disord 32 169-177, 1994 Loo H, Malka R, Defance R, et al Tianeptine and amitriptyline controlled double-blind trial in depressed alcoholic patients. Neuropsychobiology 19 79-85, 1988... 

Murck H, Nickel T, Kunzel H, Antonijevic IA, Schill J, Zobel A, Steiger A, Sonntag A, Holsboer F (2003) State markers of depression in sleep EEG dependency on drug and gender in patients treated with tianeptine or paroxetine. Neuropsychopharmacology 28 348-358... 

Ginestet D. Efficacy of tianeptine in major depressive disorders with or without melancholia. Eur Neuropsychopharmacol 1997 7Suppl 3 8341-5. 

Wilde Ml, Benfield P. Tianeptine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in depression and coexisting anxiety and depression. Drugs 1995 49(3) 411-39. 

Tianeptine sodium is a structurally novel, serotonin specific antidepressant. It is useful in the treatment of neurotic and reactive depressions, as well as depressive states accompanied by anxiety. 

Tianeptine, (K5)-7-(3-chloro-6-methyl-6,ll-dihydrodibenzo[c/ [l,2]lhiazepin-ll-yl-amino)heptanoic acid 5, 5-dioxide, is an antidepressant effective against anxiety accompanying mood disorders. The drug is used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. The TLC method was used to separate the photodegradation products of tianeptine [16] (Figure 14.13). 

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