Deoxyribonucleic acid selective detection

Graham D., Smith W.E., Linacre A.M.T., Munro C.H., Watson N.D., White P.C., Selective detection of deoxyribonucleic acid at ultralow concentrations by SERRS, Anal. Chem. 1997 69 4703-4707. 

Graham D, Smith WE, Linacre AMT, Muirro CH, Watson ND, White PC (1997) Selective detection of deoxyribonucleic acid at ultra low concentrations by SERRS. Anal Chem 69(22) 4703 707... 

In particular, the unique properties of polypyrrole-carbon nanotubes allowed the detection of hybridization reactions with complementary deoxyribonucleic acid sequences via a decrease in impedance [115], Alternatively, similar deoxyribonucleic acid sensors have been created from a composite of polypyrrole and carbon nanotube functionalized with carbon groups to covalently immobilize deoxyribonucleic acid into carbon nanotubes [116, 117]. Carbon nanotubes have also been incorporated into biosensors as nanotube arrays into which enzymes can be immobilized, along with a conducting polymer [118] and a polypyrrole dopan [119]. In general, the presence of carbon nanotubes tends to increase the overall sensitivity and selectivity of biosensors. 

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