Deoxyadenosine 5 -monophosphate, structure

In nature, eight common nucleotides exist, four found in DNA and four in RNA. In the standard abbreviations for DNA nucleotides, a lowercase d specifies the presence of deoxyribose. RNA nucleotides lack this designation. Nucleosides have names of one word (e.g., deoxyadenosine, cytidine, and uridine). The ending monophosphate completes the nucleotide names. Table 16.1 lists correct names for all common nucleotides and nucleosides, and Figure 16.9 shows linkages and structures for all eight nucleotides. 

Nucleotides differ from nucleosides in that they have phosphate groups attached to either the 3 or 5 position of the sugar. The structures of deoxyadenosine 5 -monophosphate,... 

These compounds illustrate the structural diversity of carbohydrates. Glucose is the most common simple sugar, whereas cellulose, which comprises wood, piant stems, and grass, is the most common carbohydrate in the piant world. Doxorubicin, an anticancer drug that has a carbohydrate ring as part of its structure, has been used in the treatment of ieukemia, Hodgkin s disease, and cancers of the breast, biadder, and ovaries. 2 -Deoxyadenosine 5 -monophosphate is one of the four nucieotides that form DNA. 

A series of phospholipid conjugates of general structure (13) and (14) of AZT and 3 -deoxyadenosine (cordycepin) have been synthesised from the corresponding phosphoramidites (15) and (16). It is envisaged that they will act as prodrugs of the parent nucleoside monophosphates which possess enhanced membrane permeability. 

Write a structural formula for the nucleotide deoxyadenosine-5 -monophosphate. 

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