Dengue infection

There is no specific medication for treatment of a dengue infection. Patients should rest and drink plenty of fluids. DHF can be effectively treated by fluid replacement therapy if an early clinical diagnosis is made. Hospitalization is frequently required in order to adequately manage DHF. 

Couvelard, A., Marianneau, R, Bedel, C., Drouet, M.T., Vachon, F., Henin, D., Deubel, V. Report of a fatal case of dengue infection with hepatitis Demonstration of dengue antigens in hepatocytes and liver apoptosis. Hum. Pathol. 1999 30 1106-1110... 

Laue T, Emmerich P, Schmitz H (1999) Detection of dengue virus RNA in patients after primary or secondary dengue infection by using the TaqMan automated amphfication system. J Clin Microbiol 37(8) 2543-2547... 

Two hemorrhagic fevers should be clearly separated from the other VHF diseases. Severe consequences of dengue infection are largely due to systemic capillary leakage syndrome and should be managed initially by brisk infusion of crystalloid, followed by albumin or other colloid if there is no response.29... 

Rosen L. Disease exacerbation caused by sequential dengue infections Myth or reality Rev Infect Dis. 1989 ll(May-Jun) S840-S842. 

Nunes EA, Rezende TM, Morals SL, Crippa JA, Dursun SM, Baker GB, et al. Qozapine treatment of patients with refractory schizophrenia, concurrent dengue infection and hematological abnormalities three case reports. Ther Adv Psychopharmacol 2013 3(2) 83-8. 

Therefore the use of oral prednisolone during the early acute phase of dengue infection was not associated with prolongation of viraemia or other AEs. Although not powered to assess efficacy, no reduction in the development of shock or other recognised complications of dengue virus infection were fotmd in this study. 

Tam DTH, Ngoc TV, Tien NTH, Kieu NTT, Thuy ITT, Thanh LTC, et al. Effects of short-coiuse oral corticosteroid therapy in early dengue infection in Vietnamese patients a randomized placebo-controlled trial. Clin Inf Dis 2012 55(9) 1216-24. 

FangX, Tan OK, Tse MS, Ooi EE (2010) A label-free immunosensor for diagnosis of Dengue infection with simple electrical measurements. Biosens Bioelectron 25 1137-1142... 

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