Dendritic supramolecular assembly

Host-guest systems made from dendritic materials have potential in the areas of membrane transport and drug delivery [68, 84, 85]. In a recent report [136] Tomalia and coworkers investigated structural aspects of a series of PAM AM bolaamphiphiles (e.g., 50) with a hydrophobic diamino do decane core unit. Fluorescence emission of added dye (nile red) was significantly enhanced in an aqueous medium in the presence of 50 unlike the cases when 51 and 52 were added (Fig. 23). Addition of anion surfactants to this mixture generated supramolecular assemblies which enhanced their ability (ca.by 10-fold) to accommodate nile red (53). Further increase in emission was noted by decreasing the pH from the normal value of 11 for PAMAM dendrimers to 7. At lower pH values the... 

Suzuki coupling reactions (solvent DMF, temp. 80 °C) and compared to the unsupported perfluoro-tagged catalyst at different catalyst concentrations. The yields using the perfluoro-tagged catalyst are significantly lower compared to the reactions were the supramolecular dendritic catalyst assembly... 

Gillies ER, Jonsson TB, Erechet JM (2004) Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers. J Am Chem Soc 126 11936-11943... 

The supramolecular assembly of dendrimers via H-bonding has been accomplished by Astruc, Boisselier, and Ornelas in which commercial dendritic poly(propylenimine) cores are rapidly and reversibly H-bonded to triallyl-or tris-amidoferrocenyl phenol dendrons these novel supramolecular assemblies were used for the electrochemical recognition of H2P04 and adenosine-triphosphate anions. ... 

Figure 11 outlines the structure of the homochiral enantiomers of the dendritic dipeptide, the CD and UV spectra as a function of temperature recorded in cyclohexane (a solvent that mimics the hydrophobic wall of the biological membrane and mediates self-assembly), and the structures of the supramolecular assemblies... 

Fig. 11 Structures of the homochiral dendritic dipeptides (a), their CD blue) and UV red) spectra recorded during self-assembly in cyclohexane (b, c), the nucleation and growth mechanism of cooperative supramolecular helical polymerization and the structures of the supramolecular assemblies (d). Modified with permission from [114]. Cop3right 2011 American Chemical Society...

Sousa-Herves A, Femandez-Megia E, Riguera R (2008) Synthesis and supramolecular assembly of clicked anionic dendritic polymers into polyion complex micelles. Chem Commun (27) 3136-3138. doi 10.1039/b805208e... 

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