Demineralized bone grafts

Bolander M, Balain G. The use of demineralized bone matrix in the repair of segmental defects augmentation with extracted matrix proteins and a comparison with autologous grafts. J Bone Joint Surg 1986 68 1264-1274. 

Rabie A, Deng Y, Samman N, Hagg U. The effect of demineralized bone matrix on the healing of intramembranous bone grafts in rabbit skull defects. J Dent Res 1996 75 1045-1051. 

Berven, S., Tay, B.K., Kleinstueck, F.S., Bradford, D.S., 2001. Clinical applications of bone graft substitutes in spine surgery consideration of mineralized and demineralized preparations and growth factor supplementation. Eur. Spine J. 10 (Suppl. 2), S169-S177. 

Bostrom MP, Seigerman DA (2005) The clinieal use of allografts, demineralized bone matrices, synthetic bone graft substitutes and osteoinductive growth factors a survey study. HSS J 1(1) 9-18... 

Allograft bone has been very extensively investigated as a commercial bone graft material. One of the first studies on the development of an injectable lysine-derived polyurethane bone graft investigated an LDI-based carrier for demineralized bone matrix [18]. An LDI-poly(p-dioxanone-co-glycolate) prepolymer was mixed with demineralized bone matrix to form a reactive putty. Implantation of the putty in an intramuscular site did not elicit an adverse inflammatory response. Several more recent studies have... 

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