Delicious octapeptide

An octapeptide, Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala, which has a delicious taste, was isolated from beef treated with papain by the use of gel filtration and ion-exchange chromatography, and filter paper electrophoresis (33) A sensory evaluation showed that this octapeptide produced synthetically also elicited a delicious taste (54) The elimination of two amino acid residues at N-terminus, Lys-Gly, led to the disappearance of the savory taste and changed it into a sour taste. This indicated that the residues, Lys-Gly are important to the savory taste. 

Beefy meaty peptide (BMP), also known as delicious peptide Enhances meat flavour. Octapeptide of the sequence Ly s-Gly-Asp-Glu-Glu- Ser-Leu-Ala. 

The delicious peptide Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala, is an octapeptide which was isolated from the gravy of beef and its primary structure was proposed in 1978 (3). It possesses a taste profile umami/sour... 

Three fragments of the delicious peptide sequence lysine-glycine, serine-leucine-alanine and aspartic acid-glutamic acid-glutamic acid possess separately umami/salty, bitter and sour taste respectively but mixtures or combinations of them produce a similar taste of that corresponding to the complete octapeptide. The synthesis of CBZ-Lys-Gly-OMe and CBZ-Ser-Leu-OMe were carried out using immobilized trypsin and thermolysin. We have studied the influence of reaction medium (pH, temperature and substrate concentration) on the yield and initial reaction rate of synthesis. 

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