Beefy meaty peptide

The first new compound to be identified that appeared to offer flavor potentiation is the Beefy Meaty Peptide (BMP). This peptide was found in a papain digest of beef by Yamasaki and Mackawa [53]. The authors identified the peptide as an octapeptide (Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala). This peptide upon synthesis and sensory evaluation was reported to have beefy flavor properties [54]. Substantial additional research has been conducted on this peptide, and Spanier and Miller [55] have reviewed much of this work. 

Confusion in the literature regarding the sensory character of the BMP and a new approach to peptide synthesis permitting larger scale synthesis, prompted van Wassenaar et al. [56] to do more a thorough sensory evaluation. They found that the BMP they synthesized and an equivalent commercial product lacked any taste. 

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The flavor enhancer monosodium glutamate (MSG) is currently used in virtually every type of savory prepared-food. Unfortunately, MSG has several deleterious side effects on a large proportion of the population. Fortunately, a naturally occurring peptide isolated from a muscle food (beef) can serve not only as a potential replacement for MSG but also as a nutritional adjuvant. The peptide, called BMP or beefy meaty peptide, acts as a flavor enhancer and is found to occur naturally in beef Chapter 6). Research on BMP suggest that it is not only non-allergenic but, by virtue of its protein composition, is a nutritionally sound replacement for MSG. 

The role of aspartic acid and glutamic acid was investigated in BMP (Beefy Meaty peptide, Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala) isolated from enzymatic digests of beef soup. The taste of BMP was affected by the sequence of acidic fragment. Sodium ion uptake of acidic dipeptides and their taste, when mixed with sodium ion, were dependent on the component and/or sequence of dipeptides containing acicHc amino acids. 

The function of acidic peptides was examined by using the peptide which was isolated from beef soup and sequenced as Lys-Gly-Asp-Glu-Glu-Ser-Leu-Ala by Yamasaki and Maekawa (5) and Tamura et al (6). According them, the peptide solution tasted just like beef soup. Spanier (7) nam this peptide as Beefy Meaty Peptide (BMP) based on its taste. 

Certain polypeptides resulting from protease digestion of proteins contribute to the typical taste of savoury foods. The DNA sequence coding for an octapep-tide known as beefy meaty peptide was cloned into yeast as a fusion with the yeast a factor to be secreted as free octapeptide into the medium which facilitated its recovery [37]. Alternatively, intracellular expression of tasty peptides... 

Beefy meaty peptide (BMP), also known as delicious peptide Enhances meat flavour. Octapeptide of the sequence Ly s-Gly-Asp-Glu-Glu- Ser-Leu-Ala. 

Wang K., Maga J.A., Bechtel P.J. Taste properties and synergisms of beefy meaty peptide./ouruo/ of Food Science, 61 837-839 (1996). 

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