Dehydrogenase aryl alcohol

Nicotinamide Adenine Dinucleotide phosphate (NADP+) Glutamate dehydrogenase, Alcohol dehydrogenase, Aryl-aldehyde dehydrogenase... 

Aryl alcohol dehydrogenase AAD14 Yn 331c 41,856 6.51 Unknown Soluble, cytoplasm... 

Putative aryl alcohol dehydrogenase AAD15 Yoll65c 15,618 5.78 Unknown Unknown... 

Figure 6 Yeast aryl alcohol dehydrogenases. The sequences of six yeast open reading frames were aligned simultaneously with the CLUSTAL W program [46], Residues are colored as in Fig. 2A and the Y-X-X-X-K motif is indicated by two black triangles. Because the open reading frames differ dramatically in size, conserved residues are also indicated in regions not present in all six sequences.

Gutierrez, A., Caramelo, L., Prieto, A., Martinez, M. J., Martinez, A. T. (1994). Anisaldehyde production and aryl-alcohol oxidase and dehydrogenase activities in hgninolytic fungi of the genus Pleurotus. Appl Environ Microbiol, 60,1783-1788. 

The second category of aldehyde dehydrogenases are efficient catalysts of the oxidation of both aryl and alkyl aldehydes to the corresponding carboxylic acids. The most well known and common of such reactions is the oxidation of acetaldehyde, derived from alcohol, to acetic acid. 

Scheme 32 Electroenzymatic reduction of ketones with alcohol dehydrogenase Rh aryl, R alkyl, CHO, CO2H, yields 92-100%, 0 - 100% ee.

Acyl aryl amidase Alcohol Dehydrogenase a-Amylase Aspartase... 

Aryl-aldehyde dehydrogenase was purified from Neurospora crassa to remove a dehydrogenase that reduces vanillin to vanillyl alcohol 23). Vanillic acid, isovanillic acid, and PCA were extracted from a fermentation broth with ethyl acetate. Reprecipitation of the isolated products increased the vanillic acid PCA ratio from 1 2 to 2.5 1 (mol/mol). Incubation of the resulting mixture with aryl aldehyde dehydrogenase, NADP, and ATP for 7 h at 30 C resulted in a 92% reduction of vanillic acid to vanillin but only a 33% reduction of PCA to protocatechualdehyde. Vanillin was extracted from the reaction with CH2CI2, affording a product with 10 mol % isovanillin as the only detected contaminant. Based on the concentration of vanillic acid in the fermentation broth, reduction of vanillic acid through purification of vanillin proceeded in 66% overall yield. 

Cytochrome P450 Alcohol dehydrogenase Aldehyde dehydrogenase Aldehyde oxidase Carboxylesterase Aiylesterase Acetylesterase Aryl 4-hydroxylase Aryl sulphatase... 

Synthesis of (S)- and (/ )-3-aryl-3-hydroxypropanoic acids using different carbonyl reductases (CR1, carbonyl reductase from Candida magnoliae CR2, alcohol dehydrogenase from Saccharomyces cerevisiae) and different nitrilases (nitrilase 1 from Synechocystis sp., nitrilase 2 from BradyrhizobiumJaponicum) [58],... 

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