From Alcohols and Derivatives

Under catalysis by a ruthenium complex, N-methylmorpholine 7V-oxide rapidly oxidizes most alcohols to the corresponding aldehyde or ketone in high yield at room temperature. Homoallylic alcohols are exceptional, undergoing conversion at a slow rate, if at all. Preferential oxidation of primary, secondary diols at the secondary centre leading to keto-alcohols has been achieved by treatment of the bis-trityl derivative with trityl tetrafluoroborate.  

A basic work-up, following a Jones oxidation (as required when amino-ketones are the desired products) is facilitated by prior complexation of chromium(ill) with 

Reagents CrOj-HMPA CrOj-Amberlyst A 26 resin DMSO TFAA NaOCl-BuJN HSO  

A new method for the oxidation of primary and secondary alkanols involves the formation and photolysis of the corresponding pyruvate esters the method is particularly useful when the products are acid or base sensitive.  

The efficiency of anodic oxidations of alcohols is controlled by the solvent (if 

The first report of a method for the selective dehydration of 1,3-diols to give ketones of type (1) has appeared the dehydration process is catalysed by a combination of rhodium(in) chloride and triphenylphosphine.  

Ueno and M. Okawara, Tetrahedron Letters, 1976, 4597. K. Saigo, A. Morikawa, and T. Mukaiyama, Bull. Chem. Soc. Japan, 1976, 49, 1656. 

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