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Deductive estimation of risk from existing knowledge

DEREK (deductive estimation of risk from existing knowledge) for Windows contains 25 chemical structural alerts associated with skin irritation. [Pg.503]

Deductive Estimation of Risk from Existing Knowledge... [Pg.13]

Cariello NF, Wilson JD, Britt BH, Wedd DJ, Burlinson B, Gombar V (2002) Comparison of the computer programs DEREK and TOPKAT to predict bacterial mutagenicity. Deductive Estimate of Risk from Existing Knowledge. Toxicity Prediction by Komputer Assisted Technology. Mutagenesis 17 321-329... [Pg.805]

The first is a rule-based system, which makes predictions for untested agents by drawing upon the human interpretation of toxicity data and biological information. That is, it captures, organizes, and applies scientific expertise that relates chemical structures with developmental toxicity. Examples of commercially available rule-based approaches include HazardExpert,23 Deductive Estimation of Risk from Existing Knowledge (DEREK),24... [Pg.158]

DEREK (Deductive Estimation of Risk from Existing Knowledge Lhasa Ltd, Leeds, UK) is a rule-based system, which examines toxicity effects of potential drugs. [Pg.131]

DEREK deductive estimation of risk from existing knowledge... [Pg.255]

DEREK DEREK (Deductive Estimation of Risk from Existing Knowledge). An expert system is based on rules. It identifies the so-called toxicophores fragments of the molecule associated with the corresponding activity) and provides the related commentary for them and references to the available information http //www.lhasalimited.org/... [Pg.339]

See other pages where Deductive estimation of risk from existing knowledge is mentioned: [Pg.484]    [Pg.183]    [Pg.517]    [Pg.205]    [Pg.231]    [Pg.806]    [Pg.809]    [Pg.180]    [Pg.149]    [Pg.433]    [Pg.3198]    [Pg.2682]    [Pg.2684]    [Pg.191]    [Pg.229]    [Pg.394]    [Pg.401]    [Pg.555]    [Pg.249]    [Pg.272]    [Pg.621]    [Pg.425]    [Pg.194]    [Pg.378]    [Pg.441]   
See also in sourсe #XX -- [ Pg.249 ]



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