Death intravenous

Of the other Strychnos alkaloids vomicine has been investigated by Ruickoldt, who finds that in mice and rabbits it causes clonic convulsions, due to stimulation above the level of the anterior corpore quad-ragemina. Convulsions can be elicited after intravenous, but not after subcutaneous, injections. The toxicity is low twelve times the convulsive dose does not cause death. No special action is exerted on blood... 

Human immune globulin intravenous (IGIV) products have been associated with renal impairment, acute renal failure, osmotic nephros s and death. Individuals with a predication to acute renal failure, such as those with preexisting renal disease, diabetes mellitus individuals older than 65 years or patients receiving nephrotoxic drugs should not be given human IGIV products... 

Stroke is the leading cause of major long-term disability in adults and the third leading cause of death in the United States. On average, a new stroke occurs every 45 seconds. Thrombolytic therapy with intravenous recombinant tissue-plasminogen activator (IV rt-PA) is the most effective treatment for acute ischemic stroke. In this chapter, we review the rationale for thrombolysis in acute ischemic stroke, clinical evidence supporting the use of thrombolytics, and the application of thrombolysis in practice. 

Bonnel RA, Villalba ML, Karwoski CB, Beitz J. Deaths associated with inappropriate intravenous colchicine administration. J Emerg Med 2002 22 385-387. 

For peritonitis, early and aggressive intravenous fluid resuscitation and electrolyte replacement therapy are essential. A common cause of early death is hypovolemic shock caused by inadequate intravascular volume expansion and tissue perfusion. 

In the early phase of serious intraabdominal infections, attention should be given to preserving major organ system function. With generalized peritonitis, large volumes of intravenous (IV) fluids are required to maintain intravascular volume, to improve cardiovascular function, and to ensure adequate tissue perfusion and oxygenation. Adequate urine output should be maintained to ensure appropriate fluid resuscitation and to preserve renal function. A common cause of early death is hypovolemic shock caused by inadequate intravascular volume expansion and tissue perfusion. 

The cell surface contains antigens, which are referred to as CD, which stands for cluster of differentiation. The antibodies are produced against a specific antigen. When administered, usually by an intravenous injection, the antibody binds to the antigen, which may trigger the immune system to result in cell death through complement-mediated cellular toxicity, or the antigen-antibody cell complex may be internalized to the cancer cell, which results in cell death. Monoclonal antibodies also may carry radioactivity, sometimes referred to as hot antibodies, and may be referred to as radioimmunotherapy, so the radioactivity is delivered to the cancer cell. Antibodies that contain no radioactivity are referred to as cold antibodies. 

Extravasation generally is defined as leakage of intravenous fluids into the interstitial tissue. It is one of the most feared complications of the administration of cytotoxic chemotherapy. While extravasation does not cause death, significant morbidity may result from local tissue destruction, and immediate management is necessary. 

Decreased fetal weight and increased fetal death were reported following single intravenous injection of pregnant rats with 241Am (activity level 90 pCi/kg or 3,330 kBq/kg) on gestation day 9 (Rommerein and Sikov 1986). The investigators indicated a tendency toward increased incidences of fetuses with anomalous ribs. 

Even though methadone treatment reduces the high mortality of intravenous addicts to about 30% of controls, a number of patients and non-patients still overdose on methadone itself (Vormefelde and Poser, 2000), although the availability of methadone itself does not appear to be linked to increases in drug-related deaths (Oliver, 2002). 

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