Cytopathogenic effect

MNTC maximum non-toxic concentration, CPE cytopathogenic effect No activity observed... 

Pine, L., Kathariou, S., Quinn, F., George, V., Wenger, J. D., and Weaver, R. E. (1991). Cytopathogenic effects in enterocyte-like Caco-2 cells differentiate virulent from aviru-lent Listeria strains. /. Clin. Microbiol. 29,990-996. 

ATCC American type of culture collection CPE Cytopathogenic effect FLU Flucanozole... 

As shown in Table 1, none of the compounds had the ability to inhibit HSV, while only quercetin-3,7-O-a-L-dirhamnoside had inhibitory activity against PI-3 in the range 8-32 pg/mL of maximum and minimum cytopathogenic effect (CPE) inhibitory concentrations, respectively. The inhibitory concentration range of this compound is on a vast scale, which resembles that of oseltamivir (32 to < 0.25 pg/mL). Besides, its maximum non-toxic concentration (MNTC) (64 pg/mL) was observed to be better than oseltamivir (32 pg/mL). 

Harvest the recombinant virus when full cytopathogenic effect (CPE) is observed in the culture by centrifuging the cell culture for 10 min at 2000 rpm (+800g). In general, CPE is already visible after 3 1 d full CPE takes approx 6 d. 

In addition, the antiviral activity of several other kinds of natural products was also reported. Terpenoids caesahnin B and bonducellpin D from the seeds of traditional Chinese medicinal plant Caesalpinia minax exhibited inhibitory activities on the PI-3 virus in vitro by cytopathogenic effects (CPE) reduction assay (Jiang et al. 2002). Hippomanin A from Phyllanthus urinaria Linnea (Euphorbiaceae), which is a commonly used traditional medicinal plant in oriental countries, exhibited antiviral activity against HSV-2 but not HSV-1 infection (Fig. 3.7 Yang et al. 2007). 

MNTCs Maximum non-toxic concentrations CPE Cytopathogenic effect HSV-1 Herpes simplex virus Type-1 iPI-3 Parainfluenza-3 virus Max Maximum Min Minimum - Not done activity observed... 

Henle, G., Girardi, A., and Henle, W., 1955, A non-transmissible cytopathogenic effect in influenza virus in tissue culture accompanied by formation of noninfec-tious hemagglutinin, J. Exp. Med. 101 25. 

Poxvirus Cytopathogenicity Effects on Cellular Macromolecular Synthesis... 

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