Cyclopentolate properties

The answer is c. (Hardman, pp 156-158.) A wide variety of clinical conditions are treated with antimuscarinic drugs. Dicyclomine hydrochloride and methscopolamine bromide are used to reduce Gl motility, although side effects—dryness of the mouth, loss of visual accommodation, and difficulty in urination—may limit their acceptance by patients. Cyclopentolate hydrochloride is used in ophthalmology for its mydriatic and cycloplegic properties during refraction of the eye. Trihexyphenidyl hydrochloride is one of the important antimuscarinic compounds used in the treatment of parkinsonism. For bronchodilation in patients with bronchial asthma and other bronchospastic diseases, ipratropium bromide is used by inhalation. Systemic adverse reactions are low because the actions are largely confined to the mouth and airways. 

Cyclopentolate, an anticholinergic agent with mydriatic and cycloplegic properties (2 drops of 0.5% solution), is used in diagnostic procedures requiring mydriasis and cyclople-gia (see also Figure 69). 

Drug abuse Anticholinergic drugs are subject to abuse because of psychotropic, hallucinogenic, and euphoriant properties [46 ] and have been reported with cyclopentolate [47 ]. 

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