Cyclopentane, acetyl methyl

Cyclohexene-l,4-dione, 2,3,5-tiichloro-3, 6-bis(l,l-dimethylethyl)- [5-Cyclo-hexcne-1,4-dione, 2,3,5-tnchloio-3,6-dwert-butyl-], 55, 33 Cyclopentadiene, 55, 15,16 Cyclopentane acetyl-,55,25 Cyclopentane 1-cyano-l-phenyl-, 55,94 Cyclopentane methyl-, 55, 62 Cyclopropane, 1-acetyl-l-phenyl-, 55 94... 

PENTAMETHYL-, 56, 1 Cyclopentane, acetyl-, 55, 25 Cyclopentane, 1-cyano-l-phenyl-, 55, 94 Cyclopentane, methyl-, 55, 62 Cyclopentanol, p-toluene.sulfonate, 55, 112 Cyclopentene, 56, 34 58, 73 2-Cyclopenten-l-one, 2,5-dialkyl-, 58, 62 CYCLOPENTENONES, 58, 56 Cyclopropane, 1-acetyl-l-phenyl-, 55, 94 Cyclopropane, 1, l-dibromo-2,2-diphenyl-, 56,32... 

The donor-acceptor acyl chloride-aluminium chloride complex is not only an electrophilic reagent but also a hydride ion acceptor (oxidizing reagent). The best hydride donors are the saturated hydrocarbons, specially those containing a tertiary carbon atom. The acylation of cyclohexane is an old and well-known reaction giving acetyl-methyl-cyclopentene and/or -cyclopentane. 26,27 the yields are low because the solvent used was either cyclohexane itself or small quantities of chloroform. in our hands, we found that the reaction carried out in methylene chloride solution ( IM) led to the l-acetyl-2-methylcyclopentene and l,3-diacetyl-2-methylcyclopentene Z in good yields. A cleaner reaction also occurred from methylcyclopentane. The ratio of ys could be changed by modification of the reaction conditions (see Table 1) (overall yields of the hydrocarbons functionalization were around 75-80 %). 

Cyclopentane, 1-cyano-l-phenyl-, 55, 94 Cyclopentane, methyl-, 55, 62, 112 Cyclopropane, 1-acetyl-1-phenyl-, 55, 94... 

Acetyl- V/lc, 168 l-Formyl-6-methyl- VII/1, 130 Cyclopentan 3-Oxo-l-(2-propinyl)-E19c, 181 (En-on + Allen-SnR3) Cyclopenten 1-Acryloyl- Vll/2a, 436 l-Cyclopropyl-3-oxo-E17b, 1349f. (cycl, En/R —Li + Br —C3H5)... 

Cyclohexan 1,3-Dioxo-2-methyl-2-(1-methyl-1-nitro-ethyl)- E19a, 746 (Dion A Nitro-alkan) Cyclopentan 2-Acetyl-2-(1-methyl-l-nitro-ethyl)-l-oxo- E19a, 1128 (R-X A R-M)... 

Use of the chiral carbon pool for cyclopentenone preparation is also known. The fungal metabolite terrein [88] was selectively monoacetylated and then reduced with chromous chloride to enone [89]. Acetylation and olefin cleavage with ruthenium tetroxide aiwi sodium periodate led to aldehyde [90], which was readily decarbonylated to [65] (51). An alternative route (52) began with the less common S,S-tartaric acid [91], converted in four steps to diiodide [92]. Dialkylation of methyl methylthiomethyl sulfoxide with [92] gave the cyclopentane derivative [93]. Treatment of [93]... 

Methyl-cyclopentane-1,2-dione, which exists mainly in the enolic form (33), has been studied in connection with the synthesis of compounds related to Jasmone. Its acetylation gave the mono-enol acetate (34) which by subsequent ketalization and alkaline hydrolysis gave the monoketal (35), which reacted normally with Grignard reagents [26]. On the other hand, the mono-enamine formed from (33) with pyrrolidine has the structure (36) [261, 262] (Fig. 9.17). 

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