1-Cyclohexene-1-carboxaldehyde, 3-hydroxy

Cyclohexene-1-carboxaldehyde, 3-hydroxy-, 67, 205 Cyclohexene, 4-( 1,1 -dimethylethyI)-1 -ethenyl- (33800-81-6), 68, 116 1-Cyclohexene-1-methanol, 4-(1-methyethenyl)-, 67, 176... 

HYDROXY-1-CYCLOHEXENE-1-CARBOXALDEHYDE 1-CYCLOHEXENE-1 -CARBOXALDEHYDE, 3-HYDROXY- (67252-14-6), 67, 205 (S)-(+)-3-HYDROXY-2,2-DIMETHYLCYCLOHEXANONE Cyclohexanone, 3-hydroxy-2,2-dimethyl-, (S)- (87655-21-8), 68, 56 Hydroxylamine, N-phenyl-, 67, 187 a-Hydroxylation of ketones, 66, 138... 

HYDROXY-l-CYCLOHEXENE-1-CARBOXALDEHYDE (1-Cyclohexene-1-carboxaldehyde, 3-hydroxy-)... 

A considerable number of electrophiles were used, and the dithiane route found great utility for the syntheses of simple monofunctional compounds as well as for polyfunctional molecules, for which the dithiane moiety affords an invaluable temporary protection of a future carbonyl group. Some experimental procedures published in Organic Syntheses — cyclobutanone [277] and 3-hydroxy-l-cyclohexene-l-carboxaldehyde [278] — are illustrative. A similar route to aldehydes [279] makes use of sym-trithiane as a formyl anion equivalent. 

A third type of alkali-sensitive glycoside was described by Kuhn and Lowin 1941.13 Picrocrocin [(—)-4-hydroxy-2,6,6-trimethyl-l-cyclohexene-l-carboxaldehyde-(4 — 1) /3-D-glucopyranoside] (VIII), the bitter principle of saffron, was observed to decompose in aqueous alkali with the formation of D-glucose and the unsaturated aglucon safranal (2,6,6-tri-... 

Four of the last five entries in this volume are convenient procedures to make functionalized molecules that are useful precursors to more complex structures METHYL 7-HYDROXYHEPT-S-YHOATE and 4-ttTH0XY-3-PENTEN-2-0NE, both of which, for example, are used in making prostaglandins 3-HYDROXY-l-CYCLOHEXENE-l-CARBOXALDEHYDE and (E)-2-(l-PR0PENYL)CYCL0BUTAN0NE. The final procedure describes a remarkably selective 4-CHLORINATION OF ELECTRON-RICH BEN2EN0ID COMPOUNDS by N-chlorodialkyl amines. 

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