Curcuma longa Linn

Li-Hsun Chang, Jong, T.T., Huang, H., Nien, Y. and Chang, J.C. (2006) Supercritical carbon dioxide extraction of turmeric oil from Curcuma longa Linn and purification of turmerones. Separation and Purification Technology 47(3), 1 19-125. 

One example that can demonstrate the effectiveness and great promise of nanoencapsulation is the curcumin nanoemulsions. Curcumin is the major yellow pigment in turmeric Curcuma longa Linn). In South and Southeast Asia, curcumin preparation or turmeric has been used extensively to treat inflammatory conditions and chronic diseases (Reddy and Rao 2003). Orally administered curcumin usually has low systemic bioavailability. Only trace amounts of curcumin (or its metabolites) appear in the blood, and most of ingested curcumin is excreted in the feces. One reason is that curcumin has low solubility and does not disperse for absorption. The absorbed curcumin is rapidly metabolized in the intestine and liver to several reduction products (di-, tetra-, and hexa-hydrocurcumin and hexahydrocurcuminol) and... 

Essential oils have also been shown to be useful as anti-inflammatory agents. The anti-inflammatory and antipyretic activities of Ocimum sanctum fixed oil have been evaluated recently [220]. The results reported are consistent with the folk medicine use of different parts of this plant for the treatment of acute and chronic inflammation. The results of an investigation on the anti-inflammatory activities of flavonoids of Baphia nitida, another plant used in folk medicine, were recently reported [221]. The flavo no id-rich fraction of the leaf, obtained by a chromatographic process, was formulated into an ointment and exhibited significant antiinflammatory activity in several rodent inflammation models. The inhibition of tumor necrosis factor (TNF-a) and interleukin-1(3 (IL-1), mediators in many acute and chronic inflammatory diseases, by curcumin (111), a phytochemical isolated from the plant Curcuma longa Linn, was recently reported [222]. This report shows that, in vitro, curcumin (111), at 5 (J.M, inhibited lipopolysaccharide (LPS)-induced production of TNF-a and IL-1 by a human monocytic macrophage cell line. 

Prucksunand, C., B. Indrasukhsri, M. Leethochawalit, and K. Hungspreugs. 2001. Phase II clinical trial on effect of the long turmeric (Curcuma longa Linn) on healing of peptic ulcer. Southeast Asian J. Trop. Med. Public Health 32(1) 208-215. 

CCurcUma longa, linn. Reddish-yellow jHisms. M.p. 183°. Mod. sd. EtOB, AoOH. Spar. sol. EtgO, CS2. 

Sa, G. Das, T. A process for producing therapeutically active pure curcumin from Curcuma longa linn. Indian IN 190920, 2003 Chem. Abstr. 2006,145, 33794. 

Singh, G., I.P. Kapoor, P. Singh et al., 2010a. Comparative study of chemical composition and antioxidant activity of fresh and dry rhizomes of tnrmeric Curcuma longa Linn.). 

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