Crystallography Converge Protein Structures Emerge

Chromatography and Crystallography Converge Protein Structures Emerge 

Perutz was studying a much bigger molecule. In 1960, he solved the hemoglobin structure at 6 A resolution. While the primary structure was not yet established, the secondary and tertiary structures bore similarities to myoglobin. Since hemoglobin has four protein chains (two a, two p) associated but not formally bonded to each other, it has a quaternary struc- 

---