Crotalid snake venoms

Snake venoms have a diverse effect on platelets. Some promote platelet aggregation and some inhibit the aggregation. Certain crotalid venoms contain both factors. By fractiona-... 

We have isolated three IX/X-bps from the venoms of various crotalid snakes, namely T. flavoviridis (7), Deinagkistrodon acutus (20), and Bothrops jararaca (21). The amino-terminal amino acid sequences of these proteins reveal an apparent homology between the amino-terminal regions of these proteins (Fig. 7). 

Snake bite (pit vipers) Antivenin (Crotalidae) polyvalent, equine The entire dose should be given within 4 hours after the bite by the IV or IM route (1 vial = 10 mL) Minimal envenomation 2-4 vials Moderate envenomation 5-9 vials Severe envenomation 10-15 vials Additional doses may be required. Neutralizes the venom of rattlesnakes, copperheads, cottonmouths, water moccasins, and tropical and Asiatic crotalids. Serum sickness occurs in almost all patients who receive > 7 vials. 

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