Cough eucalyptus

Expectorants are the drugs which increase the production of bronchial secretion and reduce its viscosity to facilitate its removal by coughing. Expectorants can stimulate the expulsion of respiratory secretion either directly or reflexly. Certain volatile oils of plant origin such as oil of lemon, anise, eucalyptus by steam inhalation route increase the respiratory secretion by its direct action. Another compound, guaiacol, which is obtained from wood creosote or synthetically prepared, directly increase bronchial secretion and syrup tolu (Tolu balsum) act in same way. 

The taste options for hard candy are generally fruit flavours and also cough drops types (herbals, mint, eucalyptus etc.). 

Aromatic agents such as eucalyptus and menthol have decongestant effects in the nose and can be useful in short-term relief of cough. Menthol inhibits capsaicin-induced cough in normal volunteers (Morice et al. 1994), and acts on a... 

A single-blind pseudo randomized crossover trial in 42 healthy children was used to compare the effect of an inhalation of either menthol or placebo on citric acid-induced cough. It was found that cough frequency was reduced in comparison to the baseline but not to that of the placebo (Kenia et al., 2008). However, the placebo chosen was eucalyptus oil, whose main component is 1,8-cineole and known to have similar antitussive properties to menthol. 

In a randomized, placebo controlled trial of citric acid-induced cough in 20 healthy subjects, the inhalation of a combination of menthol and eucalyptus oil (75% and 25%, respectively) signi cantly decreased the cough frequency (Morice et al., 1994). 

Cineole, a monoterpene cyclic ether which is also named eucalyptol, is widely distributed in plants and is found in high concentrations in the essential oil of Eucalyptus polybractea. It is extensively used in cosmetics, for cough treatment, muscular pain, neurosis, rheumatism, asthma, and urinary stones (Wichtel, 2002). Using rat liver microsomes, 1,8-cineole is predominantly converted to 3-hydroxy-l,8-cineole, followed by 2- and then 9-hydroxycineole (Miyazawa et al., 2001b). As seen in Figure 8.7, in human liver microsomes, however, only the 2-hydroxy- and 3-hydroxy products... 

Both eucalyptus oil and eucalyptol are extensively used as expectorants and/or flavoring agents in cold and cough medicines (e.g., cough drops and syrups), vaporizer fluids, antiseptic liniments, ointments, toothpastes, and mouthwashes. Also widely used as fragrance components in soaps, detergents, creams, lotions, and perfumes, with maximum use levels of 1.0 and 1.6% in perfumes reported for eucalyptus oil and eucalyptol, re-spectively. ° Eucalyptus oil and eucalyptol are used in dentistry as components of certain root canal sealers also used as solvents for root canal flllings. 

---