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Corynehacterium diphtheriae

Bordetellapertussis, Corynehacterium diphtheriae, Vibrio cholerae). This is, to a large extent, a reflection of their inability to combat that host s deeper defences. Survival at these sites is largely due to firm attachment to the epithelial cells. Such organisms manifest disease through the production and release of toxins (see below). [Pg.80]

In several enzyme systems that catalyze the desaturation of stearic acid, oleic acid (cis-A -octadecenoic acid) is the sole product and the reaction is therefore characterized by positional and geometrical stereospecificity. The desaturating system of Corynehacterium diphtheriae has been found by Schroepfer and Bloch (1965) to have the additional property of selectively removing one particular hydrogen atom from each pair of hydrogens at carbons 9 and 10 of stearic acid. The enzyme can thus distinguish between the two hydrogen atoms attached to a carbon atom of a poly-methylene chain, and the system is a notable example of the stereospecificity of enzymatic reactions at meso carbon atoms (Levy et al., 1962). The chemical identity... [Pg.369]

In Corynehacterium diphtheriae a hemoprotein which resembles cytochrome b is formed in large quantities when the organisms are grown in the presence of high concentrations of iron. The formation of hemoprotein parallels a decrease in the elaboration of toxin, and this has led to the suggestion that the toxin is the protein part of cytochrome b, or a precursor of it. The hemoprotein, obtained by sonic disruption of the bacterial cells, resembles heart muscle cytochrome b in its reduction by succinate. The reduced form reacts slowly with oxygen but is not oxidized by cytochrome c. [Pg.318]

Corynehacterium glutamicum may have acquired its ability for amino acid overproduction by retention of ancestral genes and acquisition of new genes by horizontal gene transfer, whereas its close relatives including Corynehacterium diphtheriae must have undergone a gene loss. [Pg.447]

Clostridium perfringens Staphylococcus aureus Pasteurella tularensis Proteus vulgaris Escherichia coli Shigella dysenteriae Salmonella typhosa Corynehacterium diphtheriae Azotohacter spp. [Pg.106]


See other pages where Corynehacterium diphtheriae is mentioned: [Pg.445]    [Pg.885]    [Pg.206]    [Pg.205]    [Pg.445]    [Pg.885]    [Pg.206]    [Pg.205]    [Pg.1]    [Pg.140]   
See also in sourсe #XX -- [ Pg.67 ]




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