Corticosteroids physiological actions

The pharmacological actions of steroids are generally an extension of their physiological effects. Adrenal corticosteroids exert effects on almost every organ in the body. In normal physiological concentrations, they are... 

One of the important aspects of the biochemical evolution of Vertebrates has been the acquisition by the cells of the mesoderm of enzyme systems for the biosynthesis of new types of steroid (heteromorphic evolution). One of the physiological effects of this evolution is the ionic regulation brought about by the action of the corticosteroid hormones at the urinary tube. In the Amphibiae this action is established in conjunction with a pre-existing system, that of the regulation controlled by the adenohypophysis. 

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