Coptis japonica,

RANUNCULACEAil. (1) Coptis japonica Mak. Berberine, palmatine, columbamine, coptisine, worenine. [Pg.328]

Worenine. This alkaloid, also obtained by Kitasato from Coptis japonica was isolated as the tetrahydro-base, C,oHjg04N, which crystallises from alcohol in colourless prisms, m.p. 212-3°, and is oxidised by iodine in alcohol to worenine iodide, yellow crystals from which worenine chloride, thin orange-yellow prisms, m.p. 295° (dec.), can be obtained. Tetrahydro-worenine behaves as a tertiary base, contains methylenedioxy- but no methoxyl groups, and its absorption spectrum closely resembles that of tetrahydrocoptisine from which it differs in empirical composition by. CHj. Worenine is, therefore, represented by (XXX), the alternative position (a) for the methyl group being untenable, since a-methyltetra-hydrocoptisine obtained by Freund s method is not identical with... [Pg.344]

Lee MK, Kim HS. Inhibitory effects of protoberberine alkaloids from the roots of Coptis japonica on catecholamine biosynthesis in PC12 cells. Planta Med 1996 62 31-34. [Pg.165]

MORISHIGE, T TSUJITA, T YAMADA, Y SATO, F., Molecular characterization of the S-adenosyl-L-methionine 3 -hydroxy-A-methylcoclaurine 4 -0-methyltransferase involved in isoquinoline alkaloid biosynthesis in Coptis japonica, J. Biol. Chem., 2000, 275, 23398-23405. [Pg.178]

Lee H-S. (2002) Rat lens aldose reductase inhibitory activities of Coptis japonica root-derived isoquinoline alkaloids. JAgric Food Chem 50 7013-7016. [Pg.582]

Berberine (Fig. 3), an isoquinoline alkaloid, is used for the treatment of leisimaniasis. Its biosynthesis was potentiated in cell cultures of Coptis japonica. ... [Pg.642]

Coptis japonica Berberine Isoquinoline alkaloid Antibiotic,... [Pg.643]

Otani M, Shitan N, Sakai K, Martinoia E, Sato F, Yazaki K. (2005) Characterization of vacuolar transport of the endogenous alkaloid berberine in Coptis japonica. Plant Physiol 138 1939-1946. [Pg.649]

Berberine Berberis wilsoniae Coptis japonica Thalictrum minus... [Pg.200]

Magnoflorine Coptis japonica Corydalis incisa Eschscholzia califomica Fumaria capreolata Papaver bracteatum Papaver somniferum Thalictrum minus... [Pg.200]

Takeshita, N., Fujisawa, H Miura, H Fitchen, J. H Yamada, Y. and Sato, F. 1995. Molecular cloning and characterization of S-adenosyl-L-methionine scoulerine-9-O-methyltransferase from cultured Coptis japonica cells. Plant Cell Physiology, 36 29-36. [Pg.272]

Choi, K. B., Morishige, T., Shitan, N., Yazaki, K. and Sato, F. 2002. Molecular cloning and characterization of coclaurine N-methyl transferase from cultured cells of Coptis japonica. Journal of Biological Chemistry, 277(1) 830-835. [Pg.273]

China Coptis japonica Makino Berberine, coptisine, urbenine, worenine, palmahne, jatrorrhizine, columbamine, lumicaerulic acid.3360 This herb is toxic. Antiarrhythmic, antibacterial, antiviral, antiprotozoal, anticerebral ischemic. [Pg.260]

Coptis japonica Makino, C. teeta Wall., C. chinensis Franch. [Pg.351]

Morphine and codeine biosynthesis (Samuelsson, 1999 Herbert et al., 2000 Novak et al., 2000) Studies on the biosynthesis of morphine have been carried out mainly on cell cultures mainly of Coptis japonica and species of Thalictrum. Two enzymes (tyrosine decarboxylase and phenolase) catalyze the formation of dopamine from one molecule tyrosine. Dopamine is also the key intermediate in the biosynthesis of mescaline. [Pg.203]

Coptis japonica (Ranunculaceae) jnp 47,189 84 Coptis cjuinquefolia (Ranunculaceae) sz 46,42 92 Coptis trifolia (Ranunculaceae) phy 31, 717 92 Corydalis humosa (Papaveraceae) jcpu 20,261 89 Corydalis ochotensis (Papaveraceae) jcspt 1,63 76 Corydalis ophiocarpa (Papaveraceae) yz 98,1658 78 Fumaria capreolata (Papaveraceae) per 4,96 85 Fumaria indica (Papaveraceae) phy 15,545 76 Menispermum canadense (Menispermaceae) 11yd 34,292 71 Nandina domestica (Berberidaceae) phy 27,2143 88 Thalictrum glandulosissimum (Ranunculaceae) pm 53,498 87... [Pg.115]

As observed in a different cell system (Coptis japonica cell suspension cultures), an alternative step in berberine synthesis is the formation of the methylendioxy group at the stage of tetrahydrocolumbamine [108]. The cytochrome P450 enzyme... [Pg.86]

SATO, F TAKESHITA, N., FITCHEN, J.H., FUJ1WARA, H YAMADA, Y S-Adenosyl-L-methionine scoulerine-9-0-methyltransferase from cultured Coptis japonica cells. Phytochemistry, 1993,32, 659-664. [Pg.169]

CHOI, K.-B., MORIS1GE, T., SATO, F., Purification and characterization of coclaurine iV-methyltransferase from cultured Coptis japonica cells. Phytochemistry, 2001,56,649-655. [Pg.169]

SATO, F TSUJITA, T KATAGIRI, Y., YOSHIDA, S., YAMADA, Y Purification and characterization of S -adenosyl-L-methioninemorcoclaurine 6-0-methyltransferase from cultured Coptis japonica cells. Eur. J. Biochem., 1994, 225, 125-131. [Pg.170]

GALNEDER, E., RUEFFER, M WANNER, G TABATA, M., ZENK, M.H., Alternative final steps in berberine biosynthesis in Coptis japonica cell cultures. Plant Cell Rep., 1988, 7, 1-4. [Pg.171]

Mizuno M, KojimaH, Tanaka T, linumaM, KimuraR, Zhi-Da M, Murata H (1987) Phenolic Constituents from Seeds of Coptis japonica var. dissecta. Phytochemistry 26 2071... [Pg.66]

Amann, M., Wanner, G. and Zenk, M.H. (1986) Purification and characterisation of (S)-tetrahydroberberine oxidase from cultured Coptis japonica cells. Phytochemistry, 37,979-82. [Pg.17]

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