Controlling food intake

Berthoud HR (2002) Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 26 393 128... 

Ritter S, Dinh TT, Zhang Y. 2000. Localization of hindbrain glucoreceptive sites controlling food intake and blood glucose. Brain Res 856 37-47. 

Berthoud HR. 2002. Multiple neural systems controlling food intake and body weight. Neurosci Biobehav Rev 26 393-428. (A detailed review of the neural systems controlling food intake in response to energy sources and demands. Includes extrahypothalamic structures and circuitry)... 

Another theory, the lipostafic theory proposed by Kennedy (1950), suggested that food intake varied so as to maintain body fat stores (i.e., the setpoint ). Changes in body fat stores, reflected in signals dependent on the size of those stores (e.g., blood levels of fatty acids), controlled food intake. Indeed, it has been shown that animals with lesion... 

FIGURE 140-2. Effects of food intake on leptin concentrations and proposed feedback loops controlling food intake and leptin concentration. NPY, neuropeptide Y. 

Role of hypothalamic malonyl-CoA in controlling food intake and energy... 

Bade C, McLaughlin C, DeUa-Fera M (1986) Role of cholecystokinin and opioid peptide in control food intake. Physiol Rev 66 172-234... 

To equate obesity with gluttony is in most cases a crude oversimplification. Obesity is more likely to result from some functional defect, yet the pathogenesis of obesity remains unknown, and today the mechanism of production of obesity can be discussed only in theoretical terms. To understand such a discussion it is necessary to review briefly the mechanisms controlling food intake. 

The amount of stored fat depends on the level at which a balance is achieved between the rates of its deposition and mobilization and it has been suggested that each person has a physiologically determined set point at which energy intake and energy output are balanced. This is open to question but nevertheless it is necessary to consider the factors which control food intake, energy expenditure and the means by which they are balanced. 

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