Controlled drug release systems

Controlled drug delivery, membrane technology in, 15 847-848 Controlled drug release formulations (CDRFs), 9 51, 55 polymers in, 9 71-73 Controlled drug release systems, 9 50-51 design, 9 51-52 development, 9 55-57 intelligent, 9 56-57 in market, 9 83—85... [Pg.214]

Oral controlled drug-release systems are increasingly used for short half-life drugs to reduce peak blood levels and side-eflfects, to maintain optimum drug concentration and to stimulate patient compliance. In order to maintain a constant blood-level of the drug during an extended period, a constant in vitro drug release rate is desired. The most popular controlled-release system is the matrix tablet (Desai et al., 1965). Te Wierik et al. (1996) reported on... [Pg.453]

Hirayama, F., and Uekama, K. Cyclodextrin-based controlled drug release system. Adv. Drug Deliv. Rev. 36(1) 125-141, 1999. [Pg.101]

Optimum controlled drug release systems, for example, for medical applications, cosmetics or agriculture ... [Pg.4]

Bernkop-Schnurch, A., Scholler, S. and Biebel, R.G. (2000) Development of controlled drug release systems based on thiolated polymers. J. Control. Release 66 39-48. [Pg.120]

Bruck, S.D. Mueller, E.P. Materials and biological aspects of synthetic polymers in controlled drug release systems problems and challenges. Critical Reviews in Therapeutic Drug Carrier Systems 1988, 5 (3), 171-187. [Pg.191]

Kikic I, Sist P. Applications of SCFs to pharmaceuticals controlled drug release systems. 2nd NATO ASI on Supercritical Fluids, Kemer, Turkey, 1998. [Pg.86]

Biodegradable materials were initially used in medical applications such as sutures, prostheses, controlled drug-release systems, and vascular grafts. These applications are enabled by their biocompatibility, their ability to be absorbed by the body, and because of their mechanical properties appropriate for such applications [6]. [Pg.83]

Leuenberger, H., J. D. Bonny, and M. Kolb. 1995. Percolation effects in matrix-type controlled drug release systems. Int. J. Pharmaceut. 115 217-224. [Pg.574]

T. Lopez, P. Quintana, E. Ortiz-Islas, E. Vinogradova, J. Manjarrez, D.H. Aguilar, P. CastUlo-Ocampo, C. Magana, J.A. Azamar, Characterization of sodium phen34oin co-gelled with titania for a controlled drug-release system . Materials Characterization, 58, 823-828, (2007). [Pg.156]

FIGURE 49.10 Controlled release profiles for conventional CR tablets produced by HME and porous floating tablets produced using HME. Acetohydroxamic acid (AHA) tested in 0.01 N HCl, chlorpheniramine maleate (CPM) tested in 0.1 N HCl. (Reprinted from Fukuda, M., Peppas, N.A., and McGinity, J.W., Floating hot-melt extruded tablets for gastroretentive controlled drug release system, J. Control. Release, 115, 121-... [Pg.1144]

Eukuda, M. P eppas, N.A. McGinity, J.W. Floating hot-melt extruded tablets for gastroretentive controlled drug release system. J. Control. Release 2006,115(2), 121-129. [Pg.1150]

PEAs are a branch of relatively new polymers. Research in the biomedical field is just starting to investigate possibilities in areas such as controlled drug release systems [215], hydrogels [216], tissue engineering [217,218], and other uses like adhesives and smart materials, together with the main families of functionalized PEAs that have been developed to date [214]. [Pg.364]

Razem, D., Katusin-Razem, B. The effects of irradiation on controlled drug delivery/ controlled drug release systems. Radiat. Phys. Chem. 77, 288-344 (2008)... [Pg.253]

Silica Based Nanoparticles as Controlled Drug Release Systems... [Pg.390]

A. Controlled Drug Release Systems Based on Nano- and... [Pg.853]

APPLICATIONS OF SUPERCRITICAL FLUIDS TO PHARMACEUTICALS CONTROLLED DRUG RELEASE SYSTEMS... [Pg.291]

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