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Toxicity testing, repeat-dose control animals

OECD TG 421 and TG 422 Reproduction/ Developmental Toxicity Screening Test (with or without the Combined Repeat Dose Toxicity Study) From 2 weeks prior to mating until at least day 4 postnatally 3 dose levels plus control n = 8-10 pregnant females Fertility Pregnancy length and birth Fetal and pup growth and survival until day 3 + short-term test - limited exposure period - limited number of end-points - limited sensitivity due to number of animals... [Pg.183]

The dose levels for repeated dermal toxicity studies in animals should have at least three concentrations, including an appropriate vehicle control. Except for treatment with the test chemical, the control group should be handled in a manner identical to the test group. The highest-dose level should not produce evidence of toxicity attributable to the test chemical. [Pg.486]

See other pages where Toxicity testing, repeat-dose control animals is mentioned: [Pg.7]    [Pg.533]    [Pg.236]    [Pg.40]    [Pg.215]    [Pg.388]    [Pg.236]    [Pg.347]    [Pg.1409]    [Pg.1113]    [Pg.12]    [Pg.230]    [Pg.17]    [Pg.84]    [Pg.60]    [Pg.150]    [Pg.271]    [Pg.272]    [Pg.379]    [Pg.997]    [Pg.99]    [Pg.84]   
See also in sourсe #XX -- [ Pg.143 ]



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Animal Toxicity Test

Animal control

Animal test

Animal testing

Animal toxicity

Control testing

Control tests

Repeat-dose toxicity testing

Repeatability tests

Repeated dosing

Repeated testing

Repeated-dose

Testing, repeatability

Toxic Dose

Toxic Toxicity test

Toxicity test

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