Continuous-flow reactors microreactor technology

At Sigma-Aldrich, a pilot study was performed for the transfer of microreactor technology into large-scale production for the synthesis of 2-benzoylpyridine through a Grignard reaction [85]. They transferred the small-scale 2 ml microreactor processes to production in a stainless steel Alfa Laval Art plate reactor and achieved rapid flow rates and continuous production of 200-300 kg of 2-benzoylpyridine per day. 

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