Continuous annular chromatography

Compared to the continuous annular chromatography systems sold by Isopro International and used throughout the ORNL studies, the P-CAC units developed by Prior Separation Technology feature several design modifications which will be presented hereafter. As can be seen from Fig. 3, the P-CAC system consist of three major parts the P-CAC head, the annular column, and the drive including the control panel. Figure 3 represents a schema of the laboratory sized P-CAC used as a Research and Development tool. 

Recently, the simultaneous chromatographic inter-separation of the PGMs (platinum group metals) and base metals by continuous annular chromatography has been demonstrated [46]. The basic configuration of the P-CAC is used to separate the PGMs from base metals and to inter-separate them in the same apparatus is shown in Fig. 9. 

Continuous annular chromatography (CAC) has been the subject of several recent experimental studies (120, 121), models (122, 123) and a brief review (124). The equipment is very similar to the CRAE (Figure 7). Feed, eluent, and regeneration solutions (if necessary) are fed to fixed points or arcs at the top of an annular packed bed which rotates slowly about its axis. As the chromatogram develops, the components separate... 

Finke B, Stahl B, Pritschet M, Facius D, Wolfgang J, Boehm G. Preparative continuous annular chromatography (P-CAC) enables the large-scale fractionation of fructans. J Agric Food Chem 2002 50 4743 748. 

The concept of the continuous annular chromatography (CAC) was introduced by Martin in 1949. The packed bed of the adsorbent occupies the annular space between two coaxial cylinders. The bed rotates past a fixed port through which sample is continuously fed. The eluent percolates downward through the bed. Substances elute as helical bands due to the simultaneous axial chromatographic process and bed rotation as shown in Fig. 13. The stronger the adsorption of a given substance is, the further away... 

A study on the separation of fructose, glucose and sucrose by continuous annular chromatography on a Ca -form polystyrene-... 

Chromatographic Methods Gas-Liquid Chromatography High-Pressure Liquid Chromatography Column and Continuous Annular Chromatography... 

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