Continuous annular chromatograph

Fig. 6. Schematic presentation of a continuous annular chromatographic reactor. The sample (big arrow) and the mobile phase (small arrows) are continuously introduced from the top of the column, which rotates with the constant angular velocity co. Passing through the column, compound A is converted into the compounds B and C. Due to their different retention they split in three streams and exit at different positions from the column. (Reprinted with permission from [144])... 

Fig. 10A, B. Outlet profiles of a continuous annular chromatographic bioreactor. Sucrose (open circle) was converted into glucose (filled circle) and fructose (open square) and separated due to different retention on the stationary phase A only partial conversion was obtained and a sucrose peak can clearly be seen B a larger amount of enzyme was used and complete conversion was obtained. (Reprinted with permission from [148])...

The continuous annular chromatograph can be described mathematically by a theoretical plate approach similar to the one developed by Martin and Synge [40] and exemplified by Said [41] for stationary columns [5]. The mathematical description results in algebraic expressions for the elution position of each solute relative to the feed point and for the bandwidth of the eluting zone as a function of the elution position or other system parameters. However, a series of simplifications have to be made in order to describe the CAC with the theoretical plate concept ... 

F. Lang, 2003, A continuous annular chromatographic reactor, PhD Thesis, ETH Zurich, Switzerland. 

The benzene yields given by the data of Figures 4 and 5, 87% at 204°C and 88% at 227°C, may be compared with computed equilibrium yields of 13% and 19%, based on inlet conditions. This clearly shows the advantage of the continuous annular chromatographic reactor over, say, a tubular reactor. The comparison is not entirely straightforward, because dilution of the cyclohexane by He carrier as it disperses circumferentially shifts the equilibrium toward products this would have to be taken into account in any quantitative comparison. The data show only partial separation of benzene and cyclohexane. This partial separation must result in partial suppression of the back reaction, and must also contribute to the observed yield enhancement (in addition to the dilution effect). ... 

The continuous annular chromatographic reactor (CACR) realizes a continuous operation. The general set-up of an annular chromatograph has been explained in Chapter 5.3.2. 

Fig. 14 Conceptual diagram illustrating the operation of the continuous annular chromatographic unit.

Fig. 15 Construction details of a continuous annular chromatographic unit used at ORNL.

Fig. 16 Separation of Fe(III) and Cr(III) in a continuous annular chromatograph using 0.4 M (NH4)2S04 as the eluent.

Figure 44. Schematic of the pressurized continuous annular chromatograph.f i...

A device that achieves this goal for Uquid solutions is shown in Figure 8.3.2 (Begovich and Sisson, 1984). First developed hy Scott et al. (1976), the device, called a continuous annular chromatograph (CAC), consists of an annular hed of adsorbent particles between two concentric open cylinders of diameters 27.9 cm and 30.5 cm the radial bed thickness is -1.27 cm and the adsorbent particles are Dowex 50W-X8 ion exchange resin in Ca form, 50-60 pm in diameter. The column is 60 cm long and the resin... 

Figure 8.3.2. Schematic of the 279 nm diameter, continuous annular chromatograph (CAC-n). Reprinted, with permission, from Begovich and Sisson, AIChE ]., 30(5), 705 (1984). Copyright [1984] American Institute of Chemical Engineers (AIChE).

British thermal unit continuous annular chromatograph counteracting chromatographic electrophoresis... 

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