Equilibrium relation, constant separation factor adsorption

During the adsorption step, the binding of solute by the affinity ligand is often very tight, essentially irreversible. For Langmuir, or constant separation factor adsorption, the equilibrium relation is... 

Fig 7 4), which corresponds to the Langmuir equilibrium with separation factor rl in the Freundlich isotherm system In these cases, a constant profile of mass transfer zone is established while adsorption proceeds in a column (Fig 7 5) This is in contrast to linear isotherm systems where mass transfer zone continues to spread with increase of traveling time The reason for the formation of a constant pattern is explained as follows The speed of movement of the point on the mass transfer zone whose concentration is C, F(C), can be related to the equilibrium through the basic equation... 

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