Computer technology chemical process development

The development and application of the CPHMD method demonstrate that simulations are capturing physical reality at increasing resolution. With the explosion in computing technologies, we are just at the beginning of a new era, where in silico experimentation becomes an indispensable complement to wet lab experiments in exploring unanswered questions related to a wide variety of biological and chemical processes. 

The development of the population balance approach has done much to further our understanding of CSD transients and instabilities which are observed in the plant and the laboratory. Advances in computing and control technology which have occurred in the chemical process industry together with the recognition that on-line CSD control might be achievable has led to an increased level of interest and investigation of this area. 

Despite the recent rapid development of computer technology and numerical methods, the rate-based approach in its current realization still often requires a significant computational effort, with related numerical difficulties. This is one of the reasons the application of rate-based models to industrial tasks is rather limited. Therefore, further work is required in order to bridge this gap and provide chemical engineers with reliable, consistent, robust, and comfortable simulation tools for reactive separation processes. 

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